| [Purpose] To investigate the trends in mortality and years of life lost due to malignant neoplasms in Fengtai District of Beijing, 2005-2024. [Methods] Crude mortality rate, age-standardized mortality rate, the Potential Years of Life Lost (PYLL) and the Average Years of Life Lost (AYLL) were calculated to describe the status of mortality and years of life lost due to malignant neoplasms, and Annual Percent Change (APC) was calculated to analyze the time trends. [Results] From the year 2005 to 2024, crude mortality rate of malignant neoplasms increased from 162.78/105 to 230.48/105, and age-standardized mortality rate decreased statistically from 120.37/105 to 90.23/105 (APC=-1.185, P<0.001). Over the past 20 years, crude mortality rate of malignant neoplasms appeared to have a declining tendency in the age groups of 30-54 and 65-79, in which largest decreases of crude mortality rate occurred in males at age group of 35-39 (84.43%) and in females at 70-74 (51.21%) . The five leading causes of cancer-related death were lung, colorectum, liver, stomach and pancreas cancer, in which prostate cancer in males was ranked from 10th to 4th, with a significantly increased age-standardized mortality rate (APC=1.863, P=0.007) during the study period. Cancer PYLL mainly came from lung, liver and colorectum cancers in inhabitants at the age of 0 to 69. The AYLL of cervical cancer was 29.86 years per person, which was ranked 1st in females. [Conclusion] From 2005 to 2024, age-standardized mortality rate of malignant neoplasms demonstrated a decreasing trend in residents of Fengtai District. Lung, colorectum and liver cancer were major causes of neoplasm death. Sex-specific cancers caused a remarkably increased mortality, which suggested that networks for cancers control and prevention should be established according to diseases characteristics. |