| [Purpose] To analyze the cancer incidence and mortality in the elderly in Changsha in 2022 and trends from 2018 to 2022. [Methods ]:The data of new cancer cases and deaths were collected and organized from Changsha cancer registration areas.The data were stratified by areas and gender, and the crude incidence and mortality rate, age-standardized rate, age-specific rate were calculated. Age-standardized rates were adjusted by Chinese standard population in 2000 and Segi's population . Joinpoint 4.9 software was used to analyze the incidence and mortality trends of cancer by estimating the annual percentage change(APC).[Results] The crude cancer incidence in Changsha in 2022 was 1272.22 /105, which was higher in male (1457.83/105) than that in female(902.39/105),and higher in urban areas (1254.12/105) than that in rural areas (1088.59/105). The age-standardized incidence rate by Chinese standard population in 2000(ASIRC) was 1129.82/105, and the age-standardized incidence rate by Segi's world standard population(ASIRW) was 1104.76/105. The crude cancer mortality was 864.74/105,which was higher in male(1179.63/105) than that in female(567.23/10), and higher in urban areas (928.81/105) than that in rural areas (799.30/105). The age-standardized mortality rate by Chinese standard population in 2000 (ASMRC) was 783.44/105, and the age-standardized mortality rate by Segi's world standard population (ASMRW) was 700.94/105. In 2022, the age-specific incidence and mortality rates of cancer in the elderly in Changsha generally showed an increasing trend with increasing age. The peak of the age-specific incidence rate occurred in the 80–84 age group, while the peak of the age-specific mortality rate was observed in the ≥85 age group. The top 5 incident cancers were: lung cancer, colorectal cancer, female breast cancer, prostate cancer, and cervical cancer; while the top 5 causing deaths were lung cancer, colorectal cancer, liver cancer, prostate cancer, and female breast cancer. The trend of incidence from 2018 to 2022 was relatively stable, while it was increasing in rural areas with the APC of ASIRC 4.5% (95% CI:0.7%~8.4%). The trend of mortality was increasing from 2018 to 2022, with the APC of ASMRC 5.4% (95% CI: 2.5% ~8.4%). The APC was higher in male(5.9%, 95%CI:3.3%~8.6%) than that in female(5.2%, 95%CI:1.6%~8.9%), and higher in urban areas(6.8%, 95%CI: 4.6%~9%) than that in rural areas (4.0%, 95%CI: -0.2%~8.3%). Among the top 10 incident cancers in the elderly in Changsha from 2018 to 2022, ASIRC of brain and central nervous system tumors and lymphomas showed statistically significant increasing trends (P<0.05). Among the top 10 causing deaths cancers, ASMRC of lung cancer, colorectal cancer, female breast cancer, and lymphomas showed statistically significant increasing trends ( P<0.05). [Conclusion] The incidence and mortality of cancer in the elderly in Changsha were high in 2022, especially in male and in urban areas. The mortality rate of?cancer was increasing from 2018 to 2022, especially in rural areas. In Changsha, the cancer types with higher incidence and mortality rates include lung cancer, colorectal cancer, liver cancer, prostate cancer, breast cancer, and cervical cancer ,which should be the focus of prevention efforts. |
