| [Objective]To analysis the differences in the efficacy and safety of microwave ablation(MWA) and cryoablation(CA) in the treatment of lung tumors. [Methods]This study included 117 patients who underwent microwave ablation and cryoablation for lung tumors from July 2018 to February 2023. The differences in the incidence of complications, progression-free survival(PFS), and overall survival(OS) between the two groups were analyzed, and the influencing factors of complications were also analyzed. [Results]The median follow-up time was 35 months, the in-situ recurrence rate of tumors in the CA group was lower than that in the MWA group (3.2% vs. 14.1% P=0.029), the median PFS was 26 months and 24 months, the median OS was 35 months and 36 months, there were no significant differences in PFS and OS at 6 months, 1 year and 2 years (P>0.05）between the two groups. The CA group had lower rates of postoperative pain (7.9% vs. 34.4%, P=0.002) and postoperative fever (3.2% vs. 18.80%, P=0.029) than the MWA group, but the incidence of hemoptysis was higher (36.5% vs. 9.4%, P=0.033), postoperative pain decreased with the increase of the distance from the pleura (OR=0.878, P=0.022), and double-needle ablation had a higher incidence of postoperative pain than single-needle ablation (OR=4.868, P= 0.045). [Conclusions]CA has a higher incidence of hemoptysis than MWA, but a lower incidence of postoperative pain and fever, a lower risk of in situ recurrence, the treatment is safe and effective. |
