| Abstract Objective: To explore the prognostic role of nutrition risk screening 2002(NRS 2002) score、prognostic nutritional index(PNI) and controlling nutritional status(CONUT) score on the prognosis of the patients of the multiple myeloma(MM).Methods:The clinical data of 70 patients with multiple myeloma from June 2019 to February 2023 at the Suzhou Hospital Affiliated to Anhui Medical University were retrospectively analyzed.The best cut off point of NRS 2002 score,PNI and COUNT score were obtained by the operating characteristic (ROC) curve;Kaplan-Meier method and Cox proportional hazard regression model were used for univariate and multivariate analysis of patients' overall survival time(OS).Results:The best cut-off point of NRS 2002 score,PNI and COUNT score were 4.5, 39.92 and 5.5, respectively;There were statistical differences in age, hemoglobin, BMI, albumin and total cholesterol among different NRS2002 score groups and different PNI groups (all P < 0.05),There were statistical differences in age, plasma cell ratio, albumin level and total cholesterol among different COUNT score groups (all P < 0.05);NRS 2002 and COUNT score were negatively correlated with OS,PNI was positively correlated withOS;The univariate analysis showed that age, hemoglobin, BMI, NRS2002 score, PNI , COUNT score, total cholesterol, ISS stage, lactate dehydrogenase and plasma cell ratio were risk factors for the OS of patients with multiple myeloma (all p < 0.05),multivariate analysis showed that NRS 2002 score (P=0.003) and PNI (P=0.033) were independent risk factors affecting the OS of patients with MM.Conclusion:A high NRS2002 score, a low PNI index, and a high COUNT score generally indicate a poor prognosis in MM patients,Clinical work should be identified as early as possible, and give nutritional intervention as early as possible. |
