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| 腹部超声与甲胎蛋白联合筛查在肝癌早期中的应用与效果评估 |
| Application and effectiveness evaluation of abdominal ultrasound combined with alpha fetoprotein screening in early stage of liver cancer |
| 投稿时间：2024-10-31 修订日期：2024-12-31 |
| DOI： |
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| 中文关键词: 肝癌，腹部超声，甲胎蛋白，筛查 |
| 英文关键词:Liver cancer, Abdominal ultrasound, Alpha fetoprotein (AFP), Early detection |
| 基金项目:中国博士后科学基金,河南省中青年卫生健康科技创新优秀人才培养项目 |
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| 中文摘要: |
| 肝癌已成为全球第六大常见的癌症类型，同时也是仅次于肺癌和结直肠癌导致癌症死亡的第三大原因。本文将对全球主要国家地区肝癌筛查指南进行系统综述，同时探讨联合使用腹部超声（US）和甲胎蛋白（AFP）检测对早期肝癌筛查的最佳时间间隔，以及甲胎蛋白（ AFP）截断值的选择，为我国未来开展更大规模的肝癌筛查工作提供参考。 |
| 英文摘要: |
| Liver cancer has become the sixth most common type of cancer worldwide and the third leading cause of cancer deaths after lung and colorectal cancers. In this paper, we will systematically review the guidelines for liver cancer screening in major countries around the world, and discuss the optimal time interval for early liver cancer screening with the combined use of abdominal ultrasound (US) and alpha-fetoprotein (AFP) testing, as well as the selection of AFP cut-off values, which will serve as a reference for a larger-scale liver cancer screening program in China in the future. |
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