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| 宫颈癌患者红细胞分布宽度白蛋白比值与术中输血的关系分析 |
| Analysis of the relationship between the red blood cell distribution width and albumin ratio and intraoperative blood transfusion in patients with cervical cancer |
| 投稿时间：2024-09-27 修订日期：2024-11-27 |
| DOI： |
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| 中文关键词: 宫颈癌 红细胞分布宽度 白蛋白 术中输血 |
| 英文关键词:cervical cancer, red blood cell distribution width, albumin, intraoperative blood transfusion |
| 基金项目:陕西省重点研发计划项目(编号:2019SF-137) |
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| 摘要点击次数: 79 |
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| 中文摘要: |
| 目的 探讨宫颈癌（CC）患者红细胞分布宽度/白蛋白（RDW/ALB）与术中输血的关系分析。方法 在2019年12月至2023年5月期间有371例接根治性子宫切除术的CC患者被纳入本研究，其中有55例（14.82%）在术中进行了输血。通过Logistic模型和受试者工作特征曲线（ROC）分析术前RDW/ALB与术中输血的关系。结果 术中输血组RDW/ALB显著高于术中未输血组[0.67（0.59，0.91）vs.0.50（0.43,0.60），Z=-7.356，P＜0.001]。经Logistic单因素和多因素模型分析，在矫正了多个临床指标后，术前RDW/ALB与CC患者术中输血独立相关（P＜0.05）。经ROC分析，RDW/ALB预测术中输血的曲线下面积为0.811（95%CI：0.754～0.867），灵敏度和特异度分别为0.818、0.684，P＜0.001。结论 术前高RDW/ALB可能是宫颈癌根治性子宫切除术患者术中输血的重要危险因素。 |
| 英文摘要: |
| Objective To investigate the relationship between red blood cell distribution width/albumin (RDW/ALB) and intraoperative blood transfusion in patients with cervical cancer (CC). Methods From December 2019 to May 2023, 371 patients with CC who underwent radical hysterectomy were included in this study, of whom 55 (14.82%) underwent intraoperative blood transfusion.The relationship between preoperative RDW/ALB and intraoperative blood transfusion was analyzed by logistic model and receiver operating characteristic curve (ROC). Results The RDW/ALB in the intraoperative blood transfusion group was significantly higher than that in the non-transfusion group [0.67 (0.59, 0.91) vs. 0.50 (0.43, 0.60), Z=-7.356, P<0.001]. Logistic univariate and multivariate model analysis showed that preoperative RDW/ALB was independently correlated with intraoperative blood transfusion in CC patients after correcting for multiple clinical indicators (P<0.05). According to ROC analysis, the area under the curve of RDW/ALB in predicting intraoperative blood transfusion was 0.811 (95%CI: 0.754～0.867), and the sensitivity and specificity were 0.818 and 0.684, respectively, and the P<0.001. Conclusion Preoperative high RDW/ALB may be an important risk factor for intraoperative blood transfusion in patients undergoing radical hysterectomy for cervical cancer. |
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