Breast cancer is the most common type of cancer in women around the world, and it is also the main cause of cancer death in women. Therefore, identifying risk factors plays an important role in breast cancer diagnosis and even improving the prognosis of patients. However, in most breast cancer patients, the estrogen level in the body drops significantly due to the change of menstrual status, which leads to abnormal blood lipid level. Therefore, blood lipid level may be a changeable risk factor for breast cancer. In this review, we reviewed the studies to date on the metabolic levels of blood lipids such as major triglycerides (TG), total cholesterol (TC), low-density and high-density lipoprotein cholesterol (LDL-C and HDL-C) and the occurrence and development of breast cancer, and found that the relationship between blood lipids and breast cancer risk is an active research area. Although many studies have explored the association between blood lipids and breast cancer, the findings are still controversial. At the same time, we also found that studying the mechanism of blood lipid metabolism in breast cancer is expected to provide a new target for breast cancer treatment, further improve the prognosis and prolong the survival time of patients. Finally, monitoring the blood lipid level of breast cancer and using lipid-lowering drugs for blood lipid management have certain benefits in improving the prognosis of breast cancer patients and preventing cardiovascular diseases, but more research evidence is still needed to support these findings. |