Abstract
[Objective] To retrospectively analyze the imaging features and pathological characteristics of bronchiolar adenoma (BA) in cases where intraoperative frozen section diagnoses are challenging, with the aim of assisting in the diagnosis and surgical decision-making for such tumors.
[Methods] A cohort of patients who underwent pulmonary surgery at Yantai Yuhuangding Hospital's Department of Thoracic Surgery between January 2019 and June 2024, with intraoperative frozen section diagnoses of mucinous tumors and postoperative pathological diagnoses of bronchiolar adenoma or mucin-producing adenocarcinoma of the lung, were included. Clinical data, imaging features, and pathological characteristics were statistically analyzed.
[Results] A total of 156 patients were included in the study, with 18 in the bronchiolar adenoma group and 138 in the mucin-producing adenocarcinoma of the lung group. Non-parametric tests and chi-square tests revealed significant differences between the two groups in terms of lesion size (long axis), tumor margins, CT values, morphological features, CT signs, and intraoperative frozen section lesion size (P < 0.05).
[Conclusion] In cases of intraoperatively difficult-to-diagnose pulmonary mucinous tumors, bronchiolar adenoma tends to present with smaller lesion sizes, predominantly solid nodules, and a higher frequency of vacuolar signs on CT, compared to mucin-producing adenocarcinoma of the lung. |