术中冰冻难以诊断的细支气管腺瘤影像学特征和病理学特点回顾性分析
A retrospective analysis of the imaging characteristics and pathological features of bronchial adenomas that pose diagnostic challenges during intraoperative frozen section examination
投稿时间:2024-09-21  修订日期:2024-11-09
DOI:
中文关键词:  术中冰冻  细支气管腺瘤  粘液性肺腺癌  影像学特征  病理特征
英文关键词:Intraoperative frozen section  Bronchiolar adenoma  Mucin-producing adenocarcinoma of the lung  Imaging features  Pathological characteristics
基金项目:吴阶平医学基金会临床科研专项资助基金
作者单位邮编
李昊霖 山东第二医科大学临床医学院 26100
黄海波 烟台毓璜顶医院胸外科 
彭笑怒* 烟台毓璜顶医院胸外科 26400
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中文摘要:
      摘要 [目的] 回顾性分析术中冰冻难以诊断的细支气管腺瘤的影像学特征与病理学特点,为这类肿瘤的诊断和术中手术方式的选择提供帮助。 [方法] 选取2019年1月至2024年6月烟台毓璜顶医院胸外科接受肺手术,术中冰冻病理诊断为粘液性肿瘤,术后病理为细支气管腺瘤和粘液性肺腺癌的患者,对其临床资料、影像学特征和病理学特点等进行统计学分析。 [结果] 共156例患者纳入研究,其中细支气管腺瘤组18例,粘液性腺癌组138例。非参数检验与卡方检验显示细支气管腺瘤组与粘液性腺癌组之间CT中病灶长径、肿瘤边界、CT值、形态学特征、CT征象、术中冰冻病灶大小具有统计学意义(P<0.05)。 [结论] 在术中难以诊断的肺粘液性肿瘤中,与粘液性肺腺癌相比,细支气管腺瘤的长径更小,更多为实性结节,CT征象更多表现为空泡征。
英文摘要:
      Abstract [Objective] To retrospectively analyze the imaging features and pathological characteristics of bronchiolar adenoma (BA) in cases where intraoperative frozen section diagnoses are challenging, with the aim of assisting in the diagnosis and surgical decision-making for such tumors. [Methods] A cohort of patients who underwent pulmonary surgery at Yantai Yuhuangding Hospital's Department of Thoracic Surgery between January 2019 and June 2024, with intraoperative frozen section diagnoses of mucinous tumors and postoperative pathological diagnoses of bronchiolar adenoma or mucin-producing adenocarcinoma of the lung, were included. Clinical data, imaging features, and pathological characteristics were statistically analyzed. [Results] A total of 156 patients were included in the study, with 18 in the bronchiolar adenoma group and 138 in the mucin-producing adenocarcinoma of the lung group. Non-parametric tests and chi-square tests revealed significant differences between the two groups in terms of lesion size (long axis), tumor margins, CT values, morphological features, CT signs, and intraoperative frozen section lesion size (P < 0.05). [Conclusion] In cases of intraoperatively difficult-to-diagnose pulmonary mucinous tumors, bronchiolar adenoma tends to present with smaller lesion sizes, predominantly solid nodules, and a higher frequency of vacuolar signs on CT, compared to mucin-producing adenocarcinoma of the lung.
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