| 【Abstract】Non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer. In recent years, advancements in neoadjuvant therapy have significantly improved the prognosis for NSCLC patients. However, tumor progression following treatment remains an inevitable occurrence and is influenced by various factors, including the high-density tertiary lymphoid structures (TLS) within the tumor microenvironment (TME). Therefore, further exploration of the correlation between TLS and the prognosis of NSCLC patients is warranted. Recent research indicates a significant association between TLS in TME and favorable prognoses for NSCLC patients. Additionally, TLS can serve as an independent predictive indicator for evaluating patient outcomes. This paper aims to provide a concise overview of TLS formation, maturation, and its impact on the prognosis of NSCLC patients. |
