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| 2000-2021年浙江省膀胱癌流行现状与趋势分析 |
| Incidence and Mortality and Temporal Trends of Bladder Cancer in Zhejiang Province from 2000 to 2021 |
| 投稿时间：2026-06-30 修订日期：2026-08-24 |
| DOI： |
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| 中文关键词: 肿瘤登记 膀胱癌 发病率 死亡率 |
| 英文关键词:cancer registry bladder cancer incidence mortality |
| 基金项目: |
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| 中文摘要: |
| 摘要： [目的] 分析2021年浙江省肿瘤登记地区膀胱癌发病与死亡情况以及2000—2021年的时间变化趋势。 [方法] 收集整理浙江省22个国家级肿瘤登记处提交的膀胱癌发病与死亡登记数据，分别计算膀胱癌发病和死亡粗率、中国人口标化率（中标率）、世界人口标化率（世标率）、累积率 、截缩率等指标。利用Joinpoint软件对发病和死亡趋势进行分析，计算年度变化百分比（annual percentage change, APC）和平均年度变化百分比 （average annual percentage change，AAPC）。[结果] 2021年浙江省膀胱癌粗发病率为8.65/10 万，中标率为3.82/10万，世标率为3.81/10万。膀胱癌粗死亡率为2.95/10万，中标率为 1.01/10万，世标率为1.04/10万。男性发病率和死亡率分别是女性的4.80和4.40倍。发病率和死亡率高峰在85岁及以上年龄组，且出现标化年龄别发病构成比最高峰左移。2000—2021年浙江省膀胱癌总体发病和死亡率无趋势变化。女性膀胱癌发病和死亡率均呈下降趋势，中标发病率和世标发病率的AAPC分别为-2.10%和-2.04%（P均<0.05），中标死亡率和世标死亡率的AAPC分别为-3.34%和-2.35%（P均<0.05）。城市地区发病率呈下降趋势，中标发病率和世标发病率的AAPC分别为-1.14%和-1.03%（P均<0.05）；农村地区发病率呈上升趋势，中标发病率和世标发病率的AAPC分别为2.73%和2.72%（P均<0.05）。[结论] 浙江省膀胱癌存在性别、地区和年龄流行差异，且出现发病年龄前移的趋势。
主题词: 膀胱肿瘤；肿瘤登记；发病率；死亡率 |
| 英文摘要: |
| Abstract：[Purpose]Analysis of the incidence and mortality of bladder cancer of Zhejiang province in 2021 and the temporal trends from 2000 to 2021.[Methods]Collect and sort out the incidence and mortality registration data of bladder cancer submitted by 22 national cancer registries in Zhejiang province,and calculate indicators such as the crude rate of incidence and mortality , age-standardized rate by China standard population (ASR China ) and world standard population (ASR world), cumulative rate and truncated rate. Analysis of the trends on incidence and mortality using Joinpoint software ,calculate the average annual percentage change (AAPC) and annual percentage change (APC) .[Results]The crude incidence rate of Zhejiang province was 8.65 per 100 000,with ASR China 3.82 per 100 000 and ASR World 3.81 per 100 000 in 2021 . The crude mortality rate of Zhejiang province was 2.95 per 100 000,with ASR China 1.01 per 100 000 and ASR World 1.04 per 100 000 in 2021. The incidence and mortality of men were 4.80 and 4.40 times higher than those of women, respectively.The peak of incidence and mortality was in the age group of 85 years and above, and the peak of standardized age-specific incidence composition ratio shifted to the left. There were no trend change on the incidence and mortality of bladder cancer in Zhejiang province from 2000 to 2021. In terms of gender,the incidence and mortality of female demonstrated a downward trend, The AAPC for the incidence rate in ASR China and ASR World was -2.10% and -2.04% (both P < 0.05), respectively; the AAPC for the mortality rate in ASR China and ASR World was -3.34% and -2.35% (both P < 0.05), respectively.In terms of urban and rural areas,the incidence in urban areas demonstrated a downward trend ,the AAPC for the incidence rate in ASR China and ASR World was-1.14% and -1.03%(both P < 0.05), respectively. While the incidence in rural areas showed an upward trend,the AAPC for the incidence rate in ASR China and ASR World was 2.73% and 2.72%(both P < 0.05), respectively.[Conclusion]The epidemiological distributions of bladder cancer in Zhejiang province varies among different gender, area and age groups, and the age of onset tends to move forward.
Key words：cancer registry; bladder cancer; incidence; mortality |
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