| Abstract :[Objective] To analyze the status of population-based early diagnosis and screening for upper gastrointestinal cancer in Shihezi Area of the Corps from 2022 to 2024, and to grasp the changing trend of screening results. [Methods] Relevant data of population-based screening for upper gastrointestinal cancer in Shihezi Area of the Corps from 2022 to 2024 were collected. The results of endoscopic screening and pathological examination were statistically analyzed, and the detection rate and early diagnosis rate of upper gastrointestinal cancer screening were calculated. The chi-square test was used to analyze the differences in disease occurrence among different years, anatomical sites, genders, and age groups of 40-69 years old. [Results] A total of 8,274 person-times of endoscopic screening and 5,578 person-times of pathological examination were completed in Shihezi Area of the Corps from 2022 to 2024, with an overall detection rate of 1.23% and an early diagnosis rate of 66.67%. The detection rates in the three years were 1.12% (29/2595), 1.07% (27/2527), and 1.46% (46/3152), respectively; the early diagnosis rates were 62.07% (18/29), 66.67% (18/27), and 69.57% (32/46), respectively. According to the anatomical sites, the cases were divided into esophageal, cardiac, and gastric lesions, with detection rates of 0.18%, 0.15%, and 0.91%, and early diagnosis rates of 66.67%, 58.33%, and 68.00%, respectively. The detection rates in males and females were 2.05% and 0.57%, and the early diagnosis rates were 69.74% and 57.69%, respectively. Statistical analysis showed that there were significant differences in the detection rates of different lesion types among different anatomical sites and genders (P < 0.001). The screened population aged 40-69 years was divided into 6 subgroups, among which the 55-59 years age group accounted for the highest proportion (26.19%, 2167/8274), while the 40-44 years age group accounted for the lowest proportion (7.40%, 612/8274). The detection rates of each age group were 0.65%, 0.54%, 0.78%, 0.97%, 1.61%, and 3.41%, respectively; the early diagnosis rates were 50.00%, 40.00%, 62.50%, 63.64%, 86.36%, and 63.64%, respectively. Screening results indicated that there were significant differences in the detection rates of different lesion types among different age groups (P < 0.001). [Conclusion] The overall detection rate and early diagnosis rate of upper gastrointestinal cancer in Shihezi Area of the Corps showed a gradual increase from 2022 to 2024. Significant differences in the detection rate and early diagnosis rate of upper gastrointestinal cancer were observed among different anatomical sites, genders, and age groups. |