|
| 局部晚期可切除食管癌新辅助治疗研究进展 |
| Research Progress in Neoadjuvant Therapy for Locally Advanced Resectable Esophageal Cancer |
| 投稿时间：2025-08-18 修订日期：2025-10-01 |
| DOI： |
|
 |
| 中文关键词: 局部晚期可切除食管癌 新辅助治疗 生物标志物 |
| 英文关键词:Locally advanced resectable esophageal cance Neoadjuvant therapy Biomarkers |
| 基金项目:吴阶平医学基金会(320.6750.2021-16-54) |
|
| 摘要点击次数: 182 |
| 全文下载次数: 4 |
| 中文摘要: |
| 【】在局部晚期食管癌的治疗中,手术治疗占据主导地位。但单一手术治疗效果不佳,患者5年生存率较低。新辅助治疗相较于单纯手术治疗来说,可显著改善局部晚期食管癌患者的长期生存。因此,新辅助治疗成为局部晚期可切除食管癌的标准治疗。鉴于新辅助治疗模式百花齐放,到底哪种新辅助治疗是最优选择,也是目前研究及热议的话题。因此,本文就局部晚期可切除食管鳞癌及腺癌新辅助治疗的研究进展分别进行了梳理和总结。 |
| 英文摘要: |
| 【】In the treatment of locally advanced esophageal cancer, surgical therapy plays a dominant role. However, surgery alone yields suboptimal outcomes, with a low 5-year survival rate for patients. Evidence shows that adding neoadjuvant therapy to surgery significantly enhances long-term survival in locally advanced resectable esophageal cancer over surgery alone. This established benefit makes neoadjuvant therapy the current standard treatment.Given the diverse array of neoadjuvant treatment modalities available, determining the optimal choice remains a subject of ongoing research and debate. Therefore, this article reviews recent progress in neoadjuvant therapy for locally advanced resectable esophageal cancer, specifically addressing both squamous cell carcinoma and adenocarcinoma. |
|
在线阅读
查看/发表评论 下载PDF阅读器 |
|
|
|