北京市城区肺癌高危人群低剂量螺旋CT筛查依从性及其影响因素分析
Compliance and its influencing factors of low-dose computed tomography screening among high-risk population of lung cancer in urban Beijing
投稿时间:2023-07-13  修订日期:2023-11-22
DOI:
中文关键词:  肺肿瘤  筛查  低剂量螺旋CT  依从性  影响因素
英文关键词:Lung neoplasms  Screening  Low-dose computed tomography  Compliance  Influencing factor
基金项目:北京市医院管理中心“青苗”计划专项经费资助(QML20211102);北京大学肿瘤医院科研基金(2020-10)
作者单位邮编
李晴雨 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
杨雷 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
张希 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
刘硕 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
李慧超 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
李浩鑫 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
曹莉莉 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
季加孚 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
王宁* 北京大学肿瘤医院暨北京市肿瘤防治研究所 100036
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中文摘要:
      [目的] 分析2014—2019年北京市城区肺癌高危人群低剂量螺旋CT(LDCT)筛查依从性及其影响因素,为优化人群癌症筛查策略提供参考依据。[方法] 采用整群抽样方法,选取来自北京市东城、西城、朝阳、海淀、丰台和石景山共6个城区癌症早诊早治项目点的40~69岁北京市户籍居民进行问卷调查以评估癌症风险,对评估出肺癌高危人群开展LDCT筛查。采用χ2检验比较不同特征人群的LDCT筛查参与率(依从性)差异,采用多因素非条件logistic回归模型分析其影响因素。[结果] 共88 044名北京市城区居民参与调查,其中20 371人被评估为肺癌高危人群,高危率为23.1%。有10 645人接受了LDCT筛查,总体参与率为52.3%。多因素logistic回归分析显示,女性、50岁及以上年龄组、大学/大专及以上学历、存在有害职业暴露、家庭做饭时油烟较多、有被动吸烟史、自报存在精神创伤或压抑的人群LDCT筛查依从性更好,目前正在吸烟的人群依从性较差。[结论] 北京市城区肺癌高危人群的LDCT筛查依从性仍有提升空间。未来应针对不同特征人群实施更加精准的健康教育和管理策略,进一步提高高危人群的LDCT肺癌筛查依从性。
英文摘要:
      [Purpose] To analyze the compliance and its influencing factors of low-dose computed tomography (LDCT) screening among high-risk population of lung cancer in urban Beijing during 2014 to 2019, and to provide evidence for optimizing cancer prevention and control strategies. [Methods] We recruited permanent residents aged 40 – 69 years from community sites of Beijing Cancer Early Diagnosis and Treatment Project in six urban districts (Dongcheng, Xicheng, Chaoyang, Haidian, Fengtai and Shijingshan) of Beijing by cluster sampling method, and conducted questionnaire survey to assess their risk of cancer. The residents assessed as at high-risk of lung cancer were advised to have LDCT screening in designated hospitals. Chi-square tests were adopted to compare the differences in participation rate (compliance) of the LDCT screening among various groups and the multivariate unconditional logistic regression model was used to explore potential factors related to the compliance of LDCT screening. [Results] Among 88 044 residents who completed the questionnaire, 20 371 cases (23.1%) were evaluated as a high-risk individual of lung cancer. 10 645 subjects received LDCT screening, with an overall participation rate of 52.3%. The multivariate analysis showed that female, people aged over 50 years old, with university/college degree or above, history of harmful occupational exposure, much kitchen fumes when cooking at home, passive smokers, self-reported trauma or depression were more likely to take part in endoscopic screening while current smokers got poorer compliance (P<0.05 for all above). [Conclusion] There is still room for improvement in compliance of LDCT screening among high-risk population of lung cancer in urban Beijing. Precise health education and management strategies should be implemented in high-risk population with different characteristics to further improve the compliance in the future.
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