| 周 坤,黄 曙,费云华,等.2016—2025年江苏省涟水县上消化道癌早诊早治项目内镜筛查结果分析[J].中国肿瘤,2026,35(10):784-790. |
| 2016—2025年江苏省涟水县上消化道癌早诊早治项目内镜筛查结果分析 |
| Endoscopic Screening Outcomes for Upper Gastrointestinal Cancer in Lianshui County from 2016 to 2025 |
| 投稿时间：2026-04-16 |
| DOI：10.11735/j.issn.1004-0242.2026.10.A006 |
|
 |
| 中文关键词: 上消化道癌 癌前病变 筛查 早诊早治 淮河流域 江苏 |
| 英文关键词:upper gastrointestinal cancer precancerous lesions screening early diagnosis and treatment Huaihe River Basin Jiangsu |
| 基金项目:淮安市重点实验室建设科技项目（HAP202507） |
|
| 摘要点击次数: 0 |
| 全文下载次数: 0 |
| 中文摘要: |
| 摘 要：［目的］ 分析江苏省涟水县参与淮河流域上消化道癌早诊早治项目时上消化道癌的检出情况与影响因素。［方法］ 江苏省涟水县作为江苏省淮河流域农村地区观察点之一，2016—2025年间采用整群抽样的方法，抽取当地40~74岁常住居民进行上消化道癌风险评估，评估出高危人群，并结合年度筛查任务数确定内镜检查对象，进一步通过胃镜检查和病理诊断确定筛查结果。计算上消化道阳性病变检出率、早诊率、治疗率等指标。采用Logistic回归模型分析上消化道癌发病的危险因素。［结果］ 2016—2025年间，对涟水县10个乡镇开展了上消化道癌筛查，筛查出高危人群9 787人，高危率为49.38%，完成内镜检查8 252人，筛查率为84.32%。食管阳性检出率为1.41%，早诊率为79.31%；食管胃结合部和胃联合阳性检出率为0.38%，早诊率为38.71%。危险因素分析显示，男性、高龄、吸烟史、热食、食用腌制食品、有上消化道癌家族史、教育水平较低与上消化道阳性病变高风险相关 （P均＜0.05）。［结论］ 涟水县作为食管癌高发区，近10年食管癌的筛查取得良好效果，应进一步加强筛查覆盖面与随访，以期降低当地食管癌的发病率和死亡率；但是食管胃结合部与胃的阳性检出率和早诊率相对较低，食管胃结合部癌与胃癌的筛查与早诊早治水平亟待提高。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the detection rates and influencing factors of upper gastrointestinal(UGI) cancer in Lianshui County. ［Methods］ From 2016 to 2025， cluster sampling was used to recruit local residents aged 40-74 years old for UGI cancer risk assessment as part of the Huaihe River Basin Early Detection and Treatment Program. High-risk individuals were further selected for endoscopic examination based on annual screening quotas. Positive lesion detection rates， early diagnosis rates， and treatment rates were calculated. Multivariate Logistic regression was used to identify risk factors for UGI cancer. ［Results］ Over the 10-year period， screening covered 10 townships， identifying 9 787 high-risk individuals (high-risk rate was 49.38%). A total of 8 252 endoscopies were performed， with a endoscopy screening rate of 84.32%. The positive detection rate for esophageal cancer was 1.41%， with an early diagnosis rate of 79.31%. For gastroesophageal junction and gastric cancers combined， the positive detection rate was 0.38%， and the early diagnosis rate was 38.71%. Independent risk factors for positive UGI lesions included male， older age， smoking， consumption of hot food and pickled foods， family history of UGI cancer， and lower education level(all P<0.05). ［Conclusion］ Esophageal cancer screening in Lianshui has achieved favorable results， but the detection and early diagnosis rates of gastroesophageal junction and gastric cancers remain suboptimal. Enhanced coverage， follow-up， and targeted improvements in gastric cancer screening are urgently needed in this region. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |