| 张森茂,颜仕鹏,李 灿,等.2022年湖南省肿瘤登记地区肺癌流行特征和疾病负担及2015—2022年变化趋势分析[J].中国肿瘤,2026,35(7):522-531. |
| 2022年湖南省肿瘤登记地区肺癌流行特征和疾病负担及2015—2022年变化趋势分析 |
| Epidemiological Characteristics and Disease Burden of Lung Cancer in Cancer Registration Areas of Hunan Province in 2022 and Trends from 2015 to 2022 |
| 投稿时间：2026-05-07 |
| DOI：10.11735/j.issn.1004-0242.2026.07.A004 |
|
 |
| 中文关键词: 肺癌 发病率 死亡率 疾病负担 湖南 |
| 英文关键词:lung cancer incidence mortality disease burden Hunan |
| 基金项目:湖南省卫生健康委卫生健康科研课题（20257357，20257836） |
|
| 摘要点击次数: 39 |
| 全文下载次数: 6 |
| 中文摘要: |
| 摘 要：［目的］ 分析2022年湖南省肿瘤登记地区肺癌流行特征和疾病负担及2015—2022年变化趋势。［方法］ 基于2015—2022年湖南省肿瘤登记数据，计算肺癌的粗发病（死亡）率、中国人口标化发病（死亡）率［简称中标发病（死亡）率］、世界人口标化发病（死亡）率［简称世标发病（死亡）率］、年龄别发病（死亡）率以及累积发病（死亡）率等指标。运用Joinpoint回归模型分析年度变化百分比（annual percentage change，APC）、平均年度变化百分比（average annual percentage change，AAPC）以评估率的时间变化趋势。根据世界卫生组织提供的疾病负担计算方法计算因早死导致的寿命损失年（years of life lost，YLL）、因伤残导致的寿命损失年（years lived with disability，YLD）和伤残调整寿命年（disability-adjusted life year，DALY）。［结果］ 2022年湖南省肿瘤登记地区肺癌粗发病率为74.10/10万，中标发病率为40.10/10万，世标发病率为40.17/10万；肺癌粗死亡率为57.53/10万，中标死亡率为29.25/10万，世标死亡率为29.22/10万。男性中标发病率和死亡率（56.57/10万和45.16/10万）均高于女性（24.00/10万和13.79/10万）；城市地区肺癌的中标发病率和中标死亡率（45.05/10万和31.61/10万）均高于农村地区（38.54/10万和28.50/10万）。肺癌年龄别发病率随年龄增长呈现先升后降趋势，死亡率随年龄增长呈上升趋势，年龄别发病率在75~79岁年龄组达到峰值，而年龄别死亡率在80~84岁年龄组达到峰值。2015—2022年连续监测数据显示，湖南省肿瘤登记地区肺癌中标发病率呈现先升后降的阶段性变化，肺癌中标死亡率则相对稳定。2022年湖南省肿瘤登记地区肺癌DALY为273 715人年，DALY率为4.56‰，其中男性占74.35％，女性占25.65％，城市地区占25.38％，农村地区占74.62％。［结论］ 湖南省肿瘤登记地区肺癌发病率和死亡率仍相对较高，肺癌导致的人群寿命损失主要由死亡造成，应加强人群健康宣教，全面推进肺癌早筛早诊早治工作。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the epidemiological characteristics， disease burden of lung cancer and their changing trends from 2015 to 2022 in the cancer registration areas of Hunan Province. ［Methods］ Based on the cancer registration data of Hunan Province from 2015 to 2022， indicators including crude incidence (mortality) rate， age-standardized incidence (mortality) rate by Chinese standard population ［hereinafter referred to as ASIRC (ASMRC)］， age-standardized incidence (mortality) rate by world standard population ［hereinafter referred to as ASIRW (ASMRW)］， age-specific incidence (mortality) rate and cumulative incidence (mortality) rate of lung cancer were calculated. The Joinpoint regression model was used to analyze the average annual percentage change (AAPC) to evaluate the temporal trends of the rates. The years of life lost (YLL) due to premature death， years lived with disability (YLD) and disability-adjusted life year (DALY) were calculated according to the disease burden calculation method provided by the World Health Organization. ［Results］ In 2022， the crude incidence rate of lung cancer in the cancer registration areas of Hunan Province was 74.10/105， with ASIRC of 40.10/105 and ASIRW of 40.17/105； the crude mortality rate of lung cancer was 57.53/105， with ASMRC of 29.25/105 and ASMRW of 29.22/105. The ASIRC and ASMRC in males (56.57/105 and 45.16/105) were both higher than those in females (24.00/105 and 13.79/105)； the ASIRC and ASMRC in urban areas (45.05/105 and 31.61/105) were both higher than those in rural areas (38.54/105 and 28.50/105). The age-specific incidence showed a change of rising first then falling with age， while mortality rates of lung cancer showed an upward trend with age. The age-specific incidence rate peaked in the 75-79 years old group， while the age-specific mortality rate peaked in the 80-84 years old group. Continuous monitoring data from 2015 to 2022 showed that the ASIRC of lung cancer in the cancer registration areas of Hunan Province presented a phased change of rising first and then falling， while the ASMRC of lung cancer was relatively stable. In 2022， the DALY of lung cancer in the cancer registration areas of Hunan Province was 273 715 person-years， with a DALY rate of 4.56‰， among which males accounted for 74.35%， females accounted for 25.65%， urban areas accounted for 25.38%， and rural areas accounted for 74.62%. ［Conclusion］ The incidence and mortality rates of lung cancer in the cancer registration areas of Hunan Province are still relatively high， and the population life loss caused by lung cancer is mainly due to death. Health education for the population should be strengthened， and the early screening， early diagnosis and early treatment of lung cancer should be comprehensively promoted. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |