| 秦天燕,高彩云,张雁山,等.2022年甘肃省武威市恶性肿瘤流行特征及2010—2022年变化趋势分析[J].中国肿瘤,2026,35(4):266-276. |
| 2022年甘肃省武威市恶性肿瘤流行特征及2010—2022年变化趋势分析 |
| Analysis of the Epidemiological Characteristics of Cancer in Wuwei City of Gansu Province in 2022 and the Trends from 2010 to 2022 |
| 投稿时间:2025-11-27 |
| DOI:10.11735/j.issn.1004-0242.2026.04.A003 |
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| 中文关键词: 恶性肿瘤 发病率 死亡率 趋势分析 甘肃 |
| 英文关键词:malignant tumors incidence rate mortality rate trend analysis Gansu |
| 基金项目:武威市科技计划项目(WW23B02SF049);甘肃省省级人才项目(2021RCXM037) |
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| 中文摘要: |
| 摘 要:[目的] 分析2022年甘肃省武威市恶性肿瘤流行特征及2010—2022年变化趋势。[方法] 基于肿瘤登记及随访监测最新数据,整理经质量审核合格的甘肃省武威市各肿瘤登记点上报的恶性肿瘤发病、死亡及人口数据进行汇总分析。计算恶性肿瘤粗发病/死亡率、年龄别发病/死亡率、中国人口标化发病/死亡率(简称中标率)、世界人口标化发病/死亡率(简称世标率)等。采用Joinpoint对数线性回归模型计算发病率和死亡率的平均年度变化百分比(average annual percentage change,AAPC),分析时间变化趋势。[结果] 2022年甘肃省武威市恶性肿瘤新发病例数为4 677例,粗发病率为263.55/10万,中标发病率为157.49/10万;死亡病例为2 902例,粗死亡率为163.53/10万,中标死亡率为90.73/10万。男性中标发病率和中标死亡率均高于女性。恶性肿瘤的发病率和死亡率均随年龄的增长而上升,分别在75~79岁和80~84岁年龄组达到高峰。2022年甘肃省武威市恶性肿瘤发病与死亡顺位首位均为胃癌。2010—2022年甘肃省武威市恶性肿瘤中标发病率、中标死亡率、世标发病率及世标死亡率均呈下降趋势,AAPC分别为-4.45%、-6.90%、-4.70%和-6.93%。不同性别中标发病/死亡率、世标发病/死亡率也均呈下降趋势(P均<0.001);总体和女性粗发病率和粗死亡率变化趋势均无统计学意义(P均>0.05);男性恶性肿瘤粗死亡率呈现下降趋势(AAPC=-3.31%,P=0.043)。[结论] 2010—2022年甘肃省武威市恶性肿瘤标化发病率与死亡率均呈下降趋势,恶性肿瘤防控取得一定成效,但人口老龄化使得整体疾病负担的下降面临挑战,未来的恶性肿瘤防治工作需在现有成果基础上,积极应对人口结构变化,持续强化重点癌种与高危人群的综合防治工作。 |
| 英文摘要: |
| Abstract:[Purpose] To analyze the epidemiological characteristics of cancer in Wuwei City of Gansu Province in 2022 and trends from 2010 to 2022. [Methods] Based on the latest data from cancer registration and follow-up surveillance, we conducted a pooled analysis of qualified data on the incidence and mortality of malignant tumors reported by all cancer registration areas in Wuwei City, which had passed quality control. Crude incidence/mortality rate, age-specific incidence/mortality rate, age-standardized incidence/mortality rate by Chinese standard population (ASIRC, ASMRC) and world standard population (ASIRW, ASMRW) were calculated. The Joinpoint log-linear regression model was employed to calculate the average annual percentage change (AAPC) for both the age-standardized incidence and mortality rates, analyzing the temporal trends in Wuwei City. [Results] In 2022, there were 4 677 new cases of cancer in Wuwei City, with crude incidence rate of 263.55/105 and ASIRC of 157.49/105. There were 2 902 deaths, with a crude mortality rate of 163.53/105 and ASMRC of 90.73/105. The ASIRC and ASMRC were higher in male than those in female. The incidence and mortality of cancer increased with age, peaking at the age groups of 75~79 and 80~84 years old, respectively. Gastric cancer ranked the first in both incidence and morality of all malignant tumors in Wuwei City in 2022. From 2010 to 2022, the ASIRC, ASMRC, ASIRW and ASMRW of cancer all showed declining trends (AAPC=-4.45%,-6.90%, -4.70% and -6.93%). This declining trend was also observed for both male and female (all P<0.001). However, the trends in crude incidence rate and crude mortality rate were not statistically significant (both P>0.05), except for the crude mortality rate among males, which showed a decreasing trend (AAPC=-3.31%,P=0.043). [Conclusion] From 2010 to 2022, both the age-standardized incidence and mortality rates of cancer in Wuwei City showed declining trends, indicating certain achievements in cancer prevention and control. However, population aging has posed challenges to reducing the overall disease burden. Future cancer prevention and treatment efforts should build upon the existing accomplishments, actively address demographic changes, and continuously strengthen comprehensive prevention and control measures targeting key cancer types and high-risk populations. |
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