| 朱 军,邓裕山,龙思泽,等.2015—2023年川东北地区上消化道癌内镜筛查结果分析[J].中国肿瘤,2026,35(3):229-235. |
| 2015—2023年川东北地区上消化道癌内镜筛查结果分析 |
| Analysis of the Endoscopic Screening Results of Upper Gastrointestinal Cancer in Northeastern Sichuan Region from 2015 to 2023 |
| 投稿时间：2025-06-21 |
| DOI：10.11735/j.issn.1004-0242.2026.03.A008 |
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| 中文关键词: 上消化道癌 筛查 检出率 早诊率 四川 |
| 英文关键词:upper gastrointestinal cancer screening detection rate early diagnosis rate Sichuan |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 分析2015—2023年川东北地区（阆中市、苍溪县、南部县、西充县）常住居民上消化道癌（食管癌、贲门癌、胃癌）内镜筛查结果。［方法］ 基于40~69岁常住居民的内镜筛查数据，分析食管癌、贲门癌、胃癌的各级别病变检出率、阳性病例（癌前病变及以上）检出率、早期病例检出率及早诊率。采用χ2检验分析不同性别、年龄组的检出率差异，趋势性χ2检验评估 2015—2023 年的检出率时间变化趋势。［结果］ 2015—2023年共完成内镜筛查74 403人，上消化道各级别病变检出率为5.69%（4 237/74 403），其中食管、贲门、胃的各级别病变检出率分别为3.48%（2 588/74 403）、0.57%（427/74 403）、1.75%（1 302/74 403）。上消化道阳性病例检出率为1.46%（1 087/74 403），早期病例检出率为 1.26%（939/74 403），早诊率达 86.38%（939/1 087）。男性上消化道各级别病变检出率（7.54%）显著高于女性（4.28%）（P<0.001）。上消化道各级别病变检出率随年龄增长呈显著上升趋势（P均<0.001），其中 55 岁及以上人群检出率（食管 7.07%、贲门 1.04%、胃 2.08%）显著高于 55 岁以下人群。时间趋势显示，上消化道及食管各级别病变检出率呈 “2015—2020 年波动上升、2021—2023 年下降” 特征；贲门及胃各级别病变检出率 2015—2023 年整体呈下降趋势（P均<0.05）。［结论］ 川东北地区上消化道癌筛查成效显著。未来需重点提升55岁以上男性人群的筛查参与度，同时关注贲门癌与胃癌的发病趋势，进一步优化筛查策略以改善预后。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of endoscopic screening for upper gastrointestinal cancer (UGC)， including esophageal cancer， cardiac cancer， and stomach cancer， among permanent residents in the northeastern Sichuan region (Langzhong City， Cangxi County， Nanbu County， Xichong County) from 2015 to 2023. ［Methods］ Based on the endoscopic screening data of permanent residents aged 40~69 years old， the detection rates of various grades of lesions， positive cases (precancerous lesions and above)， early cases， and the early diagnosis rate of esophageal cancer， cardiac cancer， and stomach cancer were analyzed. The Chi-square (χ2) test was used to analyze the differences in detection rates between different genders and age groups， and the trend χ2 test was employed to evaluate the temporal change trend of detection rates from 2015 to 2023. ［Results］A total of 74 403 residents completed endoscopic screening from 2015 to 2023. The overall detection rate of various grades of upper gastrointestinal lesions was 5.69% (4 237/74 403)， among which the detection rates of various grades of lesions in the esophagus， cardia， and stomach were 3.48% (2 588/74 403)， 0.57% (427/74 403)， and 1.75% (1 302/74 403)， respectively. The detection rate of positive upper gastrointestinal cases was 1.46% (1 087/74 403)， the detection rate of early cases was 1.26% (939/74 403)， and the early diagnosis rate reached 86.38% (939/1 087). The detection rate of various grades of upper gastrointestinal lesions in male (7.54%) was significantly higher than that in female (4.28%) (P<0.001). The detection rate of various grades of lesions showed a significant upward trend with increasing age (all P<0.001)， and the detection rates in the population aged 55 years old and above (esophagus： 7.07%， cardia： 1.04%， stomach： 2.08%) were significantly higher than those in the population under 55 years old. Temporal trend analysis indicated that the detection rates of various grades of lesions in the upper gastrointestinal tract and esophagus showed a characteristic of “fluctuating increase from 2015 to 2020 and decrease from 2021 to 2023”； the detection rates of various grades of lesions in the cardia and stomach showed an overall downward trend from 2015 to 2023 (both P<0.05). ［Conclusion］ The screening for upper gastrointestinal cancer in the northeastern Sichuan region has achieved remarkable results. In the future， it is necessary to focus on improving the screening participation rate of males aged 55 years old and above， while paying attention to the incidence trends of cardiac cancer and gastric cancer， so as to further optimize the screening strategy and improve the prognosis. |
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