| 吴昕钰,钱 雯,何 燕,等.2016—2021年四川省成都市恶性肿瘤流行特征及其趋势分析[J].中国肿瘤,2026,35(3):192-201. |
| 2016—2021年四川省成都市恶性肿瘤流行特征及其趋势分析 |
| Trends of Cancer Incidence and Mortality in Chengdu City of Sichuan Province from 2016 to 2021 |
| 投稿时间：2025-04-03 |
| DOI：10.11735/j.issn.1004-0242.2026.03.A004 |
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| 中文关键词: 恶性肿瘤 发病率 死亡率 四川 |
| 英文关键词:malignant tumor incidence mortality Sichuan |
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| 中文摘要: |
| 摘 要：［目的］ 探讨成都市2016—2021年恶性肿瘤的流行特征及其变化趋势。［方法］ 收集整理2016—2021年成都市各肿瘤登记地区恶性肿瘤的发病、死亡数据。计算总人群、不同性别、不同年龄段人群恶性肿瘤发病和死亡的粗率、标化率（中标率、世标率）。采用Joinpoint 8.0.1软件计算恶性肿瘤发病和死亡的平均年度变化百分比（average annual percentage change， AAPC）。［结果］ 2016—2021年成都市恶性肿瘤发病率和死亡率均呈上升趋势，粗发病率由259.31/10万增长至307.45/10万，AAPC为4.05%。粗死亡率由138.38/10万增长至176.97/10万，AAPC为5.38%。发病率和死亡率均随年龄增长而增加，30岁以下人群发病率和死亡率均较低，40岁开始显著升高。高发恶性肿瘤主要是肺癌、结直肠癌、肝癌、胃癌、食管癌和乳腺癌，死亡率较高的主要是肺癌、肝癌、结直肠癌、食管癌和胃癌。［结论］ 成都市2016—2021年恶性肿瘤表现为发病率和死亡率上升、年轻化趋势、主要癌种发生变化等特点。未来应加大恶性肿瘤预防控制工作，对居民开展风险因素宣教，对高危人群及时开展恶性肿瘤筛查，提高早诊率与生存率。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends of cancer incidence and mortality in Chengdu from 2016 to 2021. ［Methods］ We calculated the crude and age-standardized incidence and mortality rates(using Chinese and world standard populations) for the total population， by sex and age group. The average annual percentage change(AAPC) of incidence and mortality rates was also computed by Joinpoint 8.0.1. ［Results］ Both the incidence and mortality rates of cancer in Chengdu showed an upward trend from 2016 to 2021. The crude incidence rate increased from 259.31/105 to 307.45/105(AAPC=4.05%)， and the crude mortality rate increased from 138.38/105 to 176.97/105 (AAPC=5.38%). Cancer incidence and mortality increased with age. The incidence and mortality rates were relatively low for those under the age of 30 years old， but rised significantly from the age of 40 years old. The most common cancers were lung， colorectal， liver， gastric， esophageal and breast cancer， while the leading causes of cancer-related death were lung， liver， colorectal， esophageal and gastric cancers. ［Conclusion］ From 2016 to 2021， Chengdu experienced rising cancer incidence and mortality， a trend toward earlier onset， and shifts in the spectrum of major cancer types. The situation calls for enhanced cancer prevention and control measures， including public education on risk factors， targeted screening for high-risk populations， and improved early diagnosis and survival rates. |
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