| 胥雪红,杜飞行,李 益,等.2021年浙江省肿瘤登记地区肾癌发病与死亡特征及2000—2021年变化趋势分析[J].中国肿瘤,2026,35(2):144-151. |
| 2021年浙江省肿瘤登记地区肾癌发病与死亡特征及2000—2021年变化趋势分析 |
| Incidence and Mortality of Kidney Cancer in Zhejiang Cancer Registration Areas in 2021 and Trends from 2000 to 2021 |
| 投稿时间：2025-06-27 |
| DOI：10.11735/j.issn.1004-0242.2026.02.A009 |
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| 中文关键词: 肾癌 发病率 死亡率 变化趋势 浙江 |
| 英文关键词:kidney cancer incidence mortality trend Zhejiang |
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| 中文摘要: |
| 摘 要：［目的］ 分析2021年浙江省肿瘤登记地区肾癌的发病与死亡特征及2000—2021年变化趋势。［方法］ 整理浙江省22个肿瘤登记处2000—2021年肾癌的数据资料，通过计算粗发病/死亡率、中国人口标化发病/死亡率（简称中标发病/死亡率）、世界人口标化发病/死亡率（简称世标发病/死亡率）、累积率及截缩率等指标来描述现状，采用Joinpoint回归模型计算中标率的平均年度变化百分比（average annual percentage change，AAPC）分析流行趋势。［结果］ 2021年浙江省肿瘤登记地区肾癌中标发病率为5.51/10万，其中男性为7.35/10万，女性为3.73/10万，城市地区为5.99/10万，农村地区为4.76/10万。0~74岁累积发病率为0.62%，35~64岁截缩发病率为9.75/10万。肾癌中标死亡率为1.01/10万，其中男性为1.38/10万，女性为0.66/10万，城市地区为1.01/10万，农村地区为1.02/10万。0~74岁累积死亡率为0.09%，35~64岁截缩死亡率为1.02/10万。发病率和死亡率均为男性高于女性，城市地区高于农村地区。发病率在25岁后随年龄增长持续快速上升，并均在65岁后增长速度开始放缓，70~79岁达峰值。死亡率在50岁后随年龄增长持续快速上升，总体和男性在85岁及以上年龄组达到峰值，女性则在80~84岁组达峰值。2000—2021年肾癌中标发病率呈逐年上升趋势（AAPC=2.79%，95％CI：1.76%~3.87%，P<0.05），农村男性增长最快（AAPC=13.63%，95％CI：9.52%~16.78%，P<0.05）。2000—2021年肾癌中标死亡率呈逐年上升趋势（AAPC=2.44%，95％CI：1.18%~3.73%，P<0.05），农村女性增长最快（AAPC=52.79%，95％CI：26.58%~71.42%，P<0.05）。［结论］ 浙江省肿瘤登记地区肾癌发病水平较高，2000—2021年发病和死亡率呈现逐年上升趋势，需引起重视。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the incidence and mortality of kidney cancer in Zhejiang cancer registration areas in 2021 and their trends from 2000 to 2021. ［Methods］ Data on kidney cancer from 22 cancer registries in Zhejiang Province from 2000 to 2021 were collected. Crude incidence and mortality rates， age-standardized rates using the Chinese standard population (ASIRC and ASMRC) and the world standard population (ASIRW and ASMRW)， cumulative rate (0~74 years old)， and truncated rate (35~64 years old) were calculated. The Joinpoint regression model was used to calculate the average annual percentage change (AAPC) to analyze temporal trends. ［Results］ In 2021， the ASIRC for kidney cancer in Zhejiang was 5.51/105 (7.35/105 for male， 3.73/105 for female； 5.99/105 in urban areas， 4.76/105 in rural areas). The cumulative incidence rate (0~74 years old) was 0.62%， and the truncated incidence rate (35~64 years old) was 9.75/105. The ASMRC was 1.01/105 (1.38/105 for male， 0.66/105 for female； 1.01/105 in urban areas， 1.02/105 in rural areas). The cumulative mortality rate (0~74 years old) was 0.09%， and the truncated mortality rate (35~64 years old) was 1.02/105. Incidence and mortality rates were higher in male than those in female， and higher in urban than those in rural areas. Incidence increased rapidly after the age of 25， slowing after the age of 65， and peaking in the age group of 70~79 years old. Mortality increased rapidly after the age of 50， peaking in the age group of ≥85 years old(except for female in the age group of 80~84 years old). From 2000 to 2021， the incidence showed a significant increasing trend(AAPC=2.79%， 95%CI： 1.76%~3.87%， P<0.05)， fastest in rural male (AAPC=13.63%， 95%CI： 9.52%~16.78%， P<0.05). Mortality also increased significantly (AAPC=2.44%， 95%CI： 1.18%~3.73%， P<0.05)， fastest in rural female(AAPC=52.79%， 95%CI： 26.58%~71.42%， P<0.05). ［Conclusion］ The incidence of kidney cancer in Zhejiang is relatively high， with both incidence and mortality showing increasing trends from 2000 to 2021， warranting attention. |
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