| 董 婷,成姝雯,袁芝佩,等.2013—2020年四川省肿瘤登记地区结直肠癌疾病负担变化趋势[J].中国肿瘤,2026,35(2):88-94. |
| 2013—2020年四川省肿瘤登记地区结直肠癌疾病负担变化趋势 |
| Trends in the Disease Burden of Colorectal Cancer in Sichuan Cancer Registration Areas from 2013 to 2020 |
| 投稿时间：2025-05-07 |
| DOI：10.11735/j.issn.1004-0242.2026.02.A002 |
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| 中文关键词: 结直肠癌 疾病负担 四川 |
| 英文关键词:colorectal cancer disease burden Sichuan |
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| 中文摘要: |
| 摘 要：［目的］ 分析四川省肿瘤登记地区2013—2020年结直肠癌的疾病负担变化情况。［方法］ 收集四川省14个县（市、区）2013—2020年结直肠癌的发病死亡数据。采用SAS 9.4计算其发病率、死亡率及其标化率；采用Excel计算早死寿命损失年（years of life lost，YLL）和平均早死寿命损失年（average years of life lost，AYLL）的，用Joinpoint 4.9.1.0计算2013—2020年各指标的年度变化百分比（annual percentage change，APC）。［结果］ 2013—2020年四川省肿瘤登记地区65岁及以上人口逐年增加。结直肠癌发病粗率从26.55/10万上升到38.21/10万（APC=4.76%，P＜0.001），标化发病率差异无统计学意义；死亡粗率从12.52/10万上升到23.45/10万（APC=7.67%，P＜0.001），标化死亡率除男性从9.87/10万上升到14.8/10万（APC=4.15%，P=0.017）外，其余人群差异均无统计学意义。YLL从16 328人年上升到24 600人年（APC=5.59%，P＜0.001），AYLL除农村从25.18人年下降到20.82人年（APC=-2.23%，P=0.011）外，其余变化差异均无统计学意义。［结论］ 2013—2020年四川省人口不断老龄化，结直肠癌疾病负担不断加重，需重点关注男性和农村人群。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the trends in the disease burden of colorectal cancer in Sichuan cancer registration areas from 2013 to 2020. ［Methods］ Data from 14 counties and districts in Sichuan Province from 2013 to 2020 were used. Incidence and mortality rates and their age-standardized rates (ASR) were calculated using SAS 9.4. Years of life lost (YLL) and average years of life lost (AYLL) were calculated using Excel. The annual percentage change (APC) for each indicator from 2013 to 2020 was calculated using Joinpoint 4.9.1.0. ［Results］ From 2013 to 2020， the population aged 65 years old and above increased. The crude incidence rate increased from 26.55/105 to 38.21/105 (APC=4.76%， P<0.001)， while the trend in the ASR was not statistically significant. The crude mortality rate increased from 12.52/105 to 23.45/105 (APC=7.67%， P<0.001). The ASR of mortality showed a statistically significant increase only in male， rising from 9.87/105 to 14.8/105 (APC=4.15%， P=0.017). The YLL increased from 16 328 person-year to 24 600 person-year (APC=5.59%， P<0.001). The AYLL showed a significant decrease only in rural areas， from 25.18 person-year to 20.82 person-year (APC=-2.23%， P=0.011). ［Conclusion］ From 2013 to 2020， Sichuan Province experienced population aging and an increasing disease burden of colorectal cancer. Greater attention should be paid to male and rural areas in colorectal cancer prevention and control efforts. |
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