| 王玲娜,吴丹红,方主未,等.2021年浙江省肿瘤登记地区宫颈癌发病、死亡现状及2000—2021年变化趋势[J].中国肿瘤,2026,35(1):41-47. |
| 2021年浙江省肿瘤登记地区宫颈癌发病、死亡现状及2000—2021年变化趋势 |
| Incidence and Mortality of Cervical Cancer in Zhejiang Cancer Registration Areas in 2021 and Trends from 2000 to 2021 |
| 投稿时间：2025-06-24 |
| DOI：10.11735/j.issn.1004-0242.2026.01.A006 |
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| 中文关键词: 宫颈癌 发病率 死亡率 流行趋势 浙江 |
| 英文关键词:cervical cancer incidence mortality trend Zhejiang |
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| 中文摘要: |
| 摘 要：［目的］ 分析2021年浙江省肿瘤登记地区宫颈癌发病、死亡现状及2000—2021年流行趋势。［方法］ 收集浙江省22个肿瘤登记处上报的宫颈癌发病与死亡资料，计算发病和死亡粗率、中国人口标化率（中标率）、世界人口标化率（世标率）、0~74岁累积率以及35~64岁截缩率等指标。根据2000年全国普查标准人口年龄构成计算中标发病率（age-standardized incidence rate by Chinese standard population，ASIRC）和中标死亡率（age-standardized mortality rate by Chinese standard population，ASMRC），根据 Segi 世界标准人口年龄构成计算世标发病率（age-standardized incidence rate by world standard population，ASIRW）和世标死亡率（age-standardized mortality rate by world standard population，ASMRW）。采用Joinpoint模型分析2000—2021年浙江省肿瘤登记地区宫颈癌发病和死亡趋势，计算年度变化百分比（annual percentage change，APC）、平均年度变化百分比（average annual percentage change，AAPC）及其95％置信区间（confidence interval，CI）。［结果］ 2021年浙江省肿瘤登记地区女性宫颈癌粗发病率为17.71/10万，ASIRC为11.17/10万，ASIRW为10.27/10万；粗死亡率为4.27/10万，ASMRC为2.11/10万，ASMRW为2.03/10万。年龄别发病与死亡率均随着年龄增长而上升，发病率在50~54岁及70~74岁组出现双高峰，死亡率在80~84岁组出现最高峰。2000—2021年ASIRC总AAPC为4.02%（95%CI：3.07%~4.96%），农村地区ASIRC（AAPC=8.40%，95%CI：6.75%~10.04%）的上升幅度高于城市（AAPC=2.71%，95%CI：1.60%~3.90%）。ASMRC的总AAPC为4.51%（95%CI：2.04%~7.71%），其中2000—2015年呈增长趋势（APC=7.24%，P＜0.05），2015—2021年趋势变化无统计学意义（APC=-2.02%，P＞0.05）。［结论］ 2000—2021年浙江省肿瘤登记地区宫颈癌的发病与死亡总体呈上升趋势，其中农村发病率的上升幅度高于城市，防治工作仍需重视。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of cervical cancer in Zhejiang cancer registration areas in 2021 and the trend from 2000 to 2021. ［Methods］ Incidence and mortality data of cervical cancer by 22 cancer registration areas in Zhejiang in 2021 were collected. Crude incidence and mortality rates， age-standardized rates by Chinese standard population and world standard population， cumulative rate (0~74 years old) and truncated rate (35~64 years old) were calculated. The age-standardized incidence rate by Chinese standard population (ASIRC) and age-standardized mortality rate by Chinese standard population (ASMRC) were calculated based on the standard population structure from the 2000 national census， while the age-standardized incidence rate by world standard population (ASIRW) and age-standardized mortality rate by world standard population (ASMRW) were computed in accordance with Segi’s world standard population structure. The Joinpoint model was used to analyze the trends of incidence and mortality of cervical cancer in Zhejiang cancer registration areas from 2000 to 2021 and calculate the annual percentage change (APC)， average annual percentage change (AAPC) and the 95% confidence interval (CI). ［Results］ In 2021， the crude incidence of cervical cancer among women in Zhejiang cancer registration areas was 17.71/105， the ASIRC was 11.17/105， and the ASIRW was 10.27/105； the crude mortality rate was 4.27/105， the ASMRC was 2.11/105， and the ASMRW was 2.03/105. Both incidence and mortality increased with age， with two peaks in the incidence rate at 50~54 years old and 70~74 years old ， and the mortality rate peaked at 80~84 years old. The AAPC of the ASIRC of cervical cancer among women in Zhejiang cancer registration areas from 2000 to 2021 was 4.02% (95%CI：3.07%~4.96%). Moreover， the increase in the rural areas incidence rate (AAPC=8.40%， 95%CI：6.75%~10.04%) was significantly higher than that in urban areas (AAPC=2.71%， 95%CI：1.60%~3.90%). The overall AAPC for ASMRC was 4.51% (95%CI：2.04%~7.71%). From 2000 to 2015， there was a growing trend (APC=7.24%， P<0.05)， and from 2015 to 2021， there was a no statistical significant change (APC=-2.02%， P>0.05). ［Conclusion］ From 2000 to 2021， both the incidence and mortality rates of cervical cancer in Zhejiang cancer registration areas showed an upward trend. The increase of incidence rate in rural areas was higher than that in urban areas， and prevention and treatment work still needs attention. |
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