| 陆文雯,陈静英,陶瑞珏,等.2021年浙江省肿瘤登记地区子宫体癌流行现状及2000—2021年趋势分析[J].中国肿瘤,2025,34(12):972-978. |
| 2021年浙江省肿瘤登记地区子宫体癌流行现状及2000—2021年趋势分析 |
| Incidence and Mortality of Corpus Uteri Cancer in Zhejiang Cancer Registration Areas in 2021 and Trends from 2000 to 2021 |
| 投稿时间：2025-04-11 |
| DOI：10.11735/j.issn.1004-0242.2025.12.A009 |
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| 中文关键词: 子宫体癌 发病 死亡 流行特征 趋势分析 浙江 |
| 英文关键词:corpus uteri cancer incidence mortality epidemiological characteristics trend analysis Zhejiang |
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| 中文摘要: |
| 摘 要：［目的］ 分析浙江省肿瘤登记地区2021年子宫体癌流行特征及2000—2021年发病率和死亡率趋势变化。［方法］ 利用浙江省肿瘤防治办公室收集的22个肿瘤登记处上报的2000—2021年子宫体癌发病和死亡资料，使用SAS 9.4和Joinpoint 5.3.0软件分别计算子宫体癌发病和死亡粗率、标化率、截缩率及累积率、年龄别率及平均年度变化百分比（average annual percentage change，AAPC）和95%置信区间（confidence interval，CI）等指标。［结果］ 2021年浙江省肿瘤登记地区子宫体癌粗发病率为12.15/10万（峰值在55~59岁组），中标和世标发病率分别为6.99/10万和6.80/10万，居女性恶性肿瘤发病顺位的第10位；子宫体癌粗死亡率为1.85/10万（峰值在85岁及以上组），中标和世标死亡率分别为0.88/10万和0.86/10万，居女性恶性肿瘤死亡顺位的第14位。2000—2021年，子宫体癌粗发病率显著上升（AAPC=3.88%，95%CI：2.94%~5.00%，P<0.001），标化后增幅减缓（中标和世标发病率AAPC分别为2.15%和2.21%，P均<0.001）；粗死亡率无显著变化（AAPC=-0.78%，95%CI：-2.25%~1.69%，P=0.311），但标化后显著下降（中标和世标死亡率AAPC分别为-2.77%和-2.75%，P均<0.05）。［结论］ 浙江省子宫体癌发病率波动上升，中年女性风险高；死亡率波动下降，老年女性风险高，城乡差异显著。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of corpus uteri cancer in Zhejiang cancer registration areas in 2021 and trends from 2000 to 2021. ［Methods］ Data on corpus uteri cancer incidence and mortality from 22 cancer registries in Zhejiang Province were collected by Zhejiang Provincial Office for Cancer Prevention and Control. SAS 9.4 and Joinpoint 5.3.0 were used to calculate crude rates， age-standardized incidence/mortality rates by Chinese and world standard population(ASIRC/ASMRC， ASIRW/ASMRW)， truncated rates， cumulative rates， age-specific rates， average annual percentage changes (AAPC)，and 95% confidence interval(CI). ［Results］ In 2021， the crude incidence rate of corpus uteri cancer was 12.15/105 (peak in the age group of 55~59 years old)， with ASIRC and ASIRW of 6.99/105 and 6.80/105， respectively， ranking 10th among female cancers. The crude mortality rate was 1.85/105 (peak in the age group of ≥85 years old)， with ASMRC and ASMRW of 0.88/105 and 0.86/105， respectively， ranking 14th among female cancer deaths. From 2000 to 2021， the crude incidence rate increased significantly (AAPC=3.88%， 95%CI： 2.94%~5.00%， P<0.001)， though the growth rate moderated after standardization (AAPC for ASIRC and ASIRW were 2.15% and 2.21%， respectively， both P<0.001). The crude mortality rate showed no significant change (AAPC=-0.78%， 95%CI： -2.25%~1.69%， P=0.311)， but the standardized mortality rates declined significantly (AAPC for ASMRC and ASMRW were -2.77% and -2.75%， respectively， both P<0.05). ［Conclusion］ The incidence of corpus uteri cancer in Zhejiang Province showed a fluctuating upward trend， with higher risk in middle-aged women， while mortality exhibited a declining trend， with higher risk in elderly women and notable urban-rural disparities. |
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