| 李笑琴,宋丽丽,王宇多,等.2021年浙江省肿瘤登记地区胃癌发病与死亡特征及2000—2021年变化趋势分析[J].中国肿瘤,2025,34(10):792-803. |
| 2021年浙江省肿瘤登记地区胃癌发病与死亡特征及2000—2021年变化趋势分析 |
| Incidence and Mortality of Gastric Cancer in Zhejiang Cancer Registration Areas in 2021 and Trends from 2000 to 2021 |
| 投稿时间：2025-05-27 |
| DOI：10.11735/j.issn.1004-0242.2025.10.A006 |
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| 中文关键词: 胃癌 发病率 死亡率 趋势分析 浙江 |
| 英文关键词:gastric cancer incidence mortality trend analysis Zhejiang |
| 基金项目:健康浙江百万人群队列（K纵20230085）；国家自然科学基金（82404341）；浙江省医药卫生科技临床研究应用项目（2022KY103） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2021年浙江省肿瘤登记地区胃癌发病与死亡特征以及2000—2021年的变化趋势。 ［方法］ 系统分析浙江省肿瘤登记数据，计算胃癌的粗发病（死亡）率、年龄别发病（死亡）率、中国人口标化率（中标率）、世界人口标化率（世标率）、平均年度变化百分比（average annual percentage change，AAPC）和年度变化百分比（annual percentage change，APC）等指标。［结果］ 2021年浙江省肿瘤登记地区胃癌新发病例数为7 602例，同期胃癌死亡4 178例，男性胃癌发病率和死亡率均明显高于女性，城市地区发病率高于农村而死亡率略低于农村。2000—2021年胃癌中标发病率从16.80/10万下降到16.08/10万，下降趋势没有统计学意义，分时间段显示，2000—2009年上升趋势明显，2009—2021年下降趋势明显；中标死亡率从13.59/10万下降到8.02/10万（AAPC=-2.62%，P<0.001）。2000—2021年男性和女性胃癌中标发病率下降趋势均未达到统计学意义；女性中标死亡率（AAPC=-2.68%，95%CI：-3.61%~ -1.68%，P<0.001）下降速度略高于男性（AAPC=-2.44%，95%CI：-3.06%~-1.61%，P<0.001）。［结论］ 2021年浙江省胃癌发病和死亡率均低于全国平均水平，2000—2021年浙江省胃癌负担整体呈下降趋势，提示浙江省胃癌的早期诊断和治疗取得了一定成效，但2021年胃癌发病率和死亡率高居癌种第6位和第4位，仍需继续坚持胃癌的防治工作。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of gastric cancer in Zhejiang cancer registration areas in 2021，and trends from 2000 to 2021. ［Methods］ The data of gastric cancer were obtained from Zhejiang cancer registration areas. The crude incidence/mortality rates， age-specific rates， and age-standardized incidence/mortality rates by Chinese standard population (ASRC) and the world standard population (ASRW) were calculated. The temporal trends were analyzed by calculating annual percentage change (APC) and average annual percentage change (AAPC). ［Results］ A total of 7 602 new cases and 4 178 deaths of gastric cancer were reported in 2021. The incidence and mortality rates of gastric cancer in men were significantly higher than those in women； the incidence rate in urban areas was significantly higher than that in rural areas， while the mortality was slightly lower than that in rural areas. From 2000 to 2021， the ASRC of incidence rate decreased from 16.80/105 to 16.08/105 (without statistical significance)： an upward trend was observed from 2000 to 2009， whereas a downward trend became apparent from 2009 to 2021. From 2000 to 2021 the ASRC of mortality rate decreased from 13.59/105 to 8.02/105 with an AAPC of -2.62% (P＜0.001). The decline rate of female mortality rate (AAPC=-2.68%， 95%CI：-3.61%~ -1.68%， P＜0.001) was slightly higher than that of male (AAPC=-2.44%， 95%CI：-3.06%~ -1.61%， P＜0.001). ［Conclusion］ In 2021， both the incidence and mortality rates of gastric cancer in Zhejiang Province were lower than the national average in China， which ranked 6th and 4th among all types of cancer. From 2000 to 2021， the overall burden of gastric cancer in Zhejiang Province showed a downward trend. |
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