| 景俊武,秦富强,王 强,等.2010—2019年河南省林州市恶性肿瘤发病与死亡趋势分析[J].中国肿瘤,2025,34(5):348-354. |
| 2010—2019年河南省林州市恶性肿瘤发病与死亡趋势分析 |
| Trends of Incidence and Mortality of Malignant Tumors in Linzhou City of Henan Province from 2010 to 2019 |
| 投稿时间：2024-12-28 |
| DOI：10.11735/j.issn.1004-0242.2025.05.A004 |
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| 中文关键词: 恶性肿瘤 发病 死亡 趋势 河南 |
| 英文关键词:cancer incidence mortality trend Henan |
| 基金项目: |
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| 摘要点击次数: 49 |
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| 中文摘要: |
| 摘 要：［目的］ 分析2010—2019年河南省林州市恶性肿瘤发病与死亡变化趋势。［方法］ 收集整理2010—2019年林州市肿瘤登记处恶性肿瘤发病死亡数据，依据数据质量评价标准，经完整性、有效性与可靠性评估后分性别、年龄和癌种计算各类恶性肿瘤的粗发病率（死亡率）及其标化率。利用Joinpoint软件计算平均年度变化百分比（average annual percentage change，AAPC），分析2010—2019年变化趋势。［结果］ 2010—2019年林州市恶性肿瘤粗发病率呈上升趋势，AAPC为2.09%（95%CI：0.58%~3.63%），调整人口年龄结构后，标化发病率趋于平稳。年龄别发病率趋势显示，恶性肿瘤发病率在15~29岁和60~69岁组呈现显著上升趋势，在70~79岁组呈显著下降趋势。不同癌种的发病率趋势显示，2010—2019年间，男、女性食管癌和胃癌标化发病率均呈现显著下降趋势，男性肺癌、前列腺癌发病率逐年上升，女性甲状腺癌、子宫体癌、子宫颈癌、肺癌、乳腺癌发病率显著上升。2010—2019年林州市恶性肿瘤粗死亡率呈上升趋势，AAPC为1.18%（95%CI：0.88%~1.48%），调整人口年龄结构后，标化死亡率呈现显著下降趋势，AAPC为-1.63%（95%CI：-1.86%~-1.40%）。年龄别死亡率变化主要表现为80岁及以上组恶性肿瘤死亡率显著上升，其他各年龄组保持下降或平稳状态。不同癌种的死亡率趋势显示，2010—2019年间，男、女性胃癌和食管癌标化死亡率呈下降趋势，而男性前列腺癌和唇、口腔及咽部恶性肿瘤死亡率上升，女性卵巢癌死亡率上升幅度较为明显。［结论］ 林州市恶性肿瘤疾病负担仍然较重，甲状腺癌、前列腺癌和肺癌等常见癌种发病率上升趋势显著。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends of incidence and mortality of malignant tumors in Linzhou City of Henan Province from 2010 to 2019. ［Methods］ The incidence and mortality data of malignant tumors of Linzhou cancer registration areas from 2010 to 2019 were collected and evaluated for data quality. The crude incidence/mortality rates and age-standardized incidence/mortality rates by Chinese standard population(ASIRC/ASMRC) were calculated by sex， age and cancer type. Joinpoint software was used to calculate the average annual percentage change (AAPC) to analyze the trends from 2010 to 2019. ［Results］ From 2010 to 2019， the crude incidence of malignant tumors in Linzhou City showed an upward trend， with an AAPC of 2.09% (95%CI： 0.58%~3.63%)， while the ASIRC tended to be stable. The incidence of malignant tumors showed a signifi-cant upward trend in the 15~29 and 60~69 age groups， and a significant downward trend in the 70~79 age group. From 2010 to 2019， the ASIRC of esophageal cancer and stomach cancer in both men and women showed a significant downward trend， while that of lung cancer and prostate cancer increased in men， and the incidences of thyroid cancer， uterus cancer， cervical cancer， lung cancer and breast cancer increased significantly in women. From 2010 to 2019， the crude mortality of malignant tumors in Linzhou showed a significant upward trend， with an AAPC of 1.18% (95%CI： 0.88%~1.48%)， while ASMRC showed a significant downward trend， with an AAPC of -1.63% (95%CI： -1.86%~-1.40%). The mortality increased in the group aged 80 and above， while the other age groups remained in a downward or stable state. From 2010 to 2019， the ASMRC of stomach cancer and esophageal cancer in both men and women showed a downward trend， while those of prostate cancer， and malignant tumors of the lip， oral cavity and pharyngeal in men increased， and that of ovarian cancer in women increased significantly. ［Conclusion］ The disease burden of malignant tumors in Linzhou City is still heavy. The incidence of common cancer types such as thyroid cancer， prostate cancer and lung cancer shows a significantly increasing trends from 2010 to 2019. |
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