| 王 强,秦富强,王晓红,等.2010—2019年河南省林州市食管癌流行特征与减寿年数变化趋势分析[J].中国肿瘤,2025,34(5):341-347. |
| 2010—2019年河南省林州市食管癌流行特征与减寿年数变化趋势分析 |
| Trends of Esophageal Cancer Epidemiologic Characteristics and Life Years Lost in Linzhou City of Henan Province from 2010 to 2019 |
| 投稿时间：2024-12-28 |
| DOI：10.11735/j.issn.1004-0242.2025.05.A003 |
|
 |
| 中文关键词: 食管癌 发病 死亡 趋势分析 疾病负担 河南 |
| 英文关键词:esophagus cancer incidence mortality trend analysis disease burden Henan |
| 基金项目: |
|
| 摘要点击次数: 36 |
| 全文下载次数: 19 |
| 中文摘要: |
| 摘 要：［目的］ 分析2010—2019年河南省林州市食管癌发病率、死亡率及减寿年数变化趋势。［方法］ 收集整理2010—2019年林州市肿瘤登记处食管癌发病和死亡资料，经数据质量评估后分性别、年龄组计算其粗发病（死亡）率及中标率、世标率。使用潜在寿命损失年（potential years of life lost，PYLL）、平均潜在寿命损失年（average potential years of life lost，APYLL）、潜在减寿率（potential years of life lost rate，PYLLR）评估食管癌对人群生存与预期寿命的影响。利用Joinpoint软件计算平均年度变化百分比（average annual percentage change，AAPC），分析2010—2019年变化趋势。［结果］ 2010—2019年林州市食管癌累计新发病例8 447例、死亡病例6 475例。全人群及男女性中标发病率与中标死亡率均呈显著的下降趋势，AAPC分别为-3.97%、-4.35%、-3.29%和-3.78%、-2.68%、-4.95%（P均<0.05）。各年龄组食管癌粗发病率及粗死亡率均呈显著下降趋势，0~49岁、50~59岁、60~69岁和70岁及以上年龄组粗发病率的AAPC分别为-9.92%、-8.27%、-1.41%和-3.86%（P均<0.05），粗死亡率的AAPC分别为-9.50%、-12.36%、-2.61%和-2.98%（P均<0.05）。2010—2019年林州市食管癌所致合计PYLL为60 880人年，APYLL为13.73人年，PYLLR为5.77‰。总体及分性别的PYLL、APYLL、PYLLR均呈逐年下降的趋势（P均<0.05）。［结论］ 2010—2019年林州市食管癌发病、死亡及潜在寿命损失均呈下降趋势，长期筛查效果显著。然而，男性群体及老年人群体的食管癌发病风险和死亡风险仍相对较高，后续应将这两类人群列为重点防治对象，制定更具针对性的防控策略。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends in incidence， mortality and potential life loss of esophageal cancer in Linzhou City of Henan Province from 2010 to 2019. ［Methods］ The data of esophageal cancer incidence and mortality from 2010 to 2019 were collected from Linzhou cancer registries. The crude incidence and mortality rates， age-standardized rates (ASR) by sex and age group， the potential years of life lost (PYLL)， average potential years of life lost (APYLL)， and potential years of life lost rate (PYLLR) were calculated. The average annual percentage change (AAPC) from 2010 to 2019 were analyzed with Joinpoint software. ［Results］ From 2010 to 2019， there were a total of 8 447 newly diagnosed cases and 6 475 deaths of esophageal cancer in Linzhou. The ASR incidence and ASR mortality of esophageal cancer in the total population， males， females all showed significant downward trends， with AAPCs of -3.97%， -4.35%， -3.29% and -3.78%， -2.68%， -4.95%， respectively (all P<0.05). The crude incidence and mortality rates in all age groups also showed significant downward trends. The AAPCs of incidence rate for the age groups of 0~49， 50~59， 60 ~ 69 ， and ≥70 years old were -9.92%， -8.27%， -1.41%， and -3.86%， respectively (all P<0.05)， and the AAPCs of mortality rate were -9.50%， -12.36%， -2.61%， and -2.98%， respectively (all P<0.05). From 2010 to 2019， the total PYLL caused by esophageal cancer was 60 880 person years， APYLL was 13.73 person years， and PYLLR was 5.77‰. The PYLL，APYLL， and the PYLLR of the total population and those stratified by sex all showed a decreasing trend (all P<0.05). ［Conclusion］ From 2010 to 2019， the incidence， mortality and potential life loss of esophageal cancer in Linzhou City all decreased， and the long-term effect and screening programs is significant. However， the risk of esophageal cancer among men and the elderly is still relatively high， indicating that more targeted prevention and control strategies should be developed. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|