| 张 硕,李道娟,刘言玉,等.2020年河北省肿瘤登记地区恶性肿瘤流行情况及疾病负担分析[J].中国肿瘤,2025,34(2):89-97. |
| 2020年河北省肿瘤登记地区恶性肿瘤流行情况及疾病负担分析 |
| Incidence， Mortality and Disease Burden of Malignant Tumors in Cancer Registration Areas of Hebei Province in 2020 |
| 投稿时间：2024-01-11 |
| DOI：10.11735/j.issn.1004-0242.2025.02.A002 |
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| 中文关键词: 恶性肿瘤 发病率 死亡率 疾病负担 伤残调整寿命年 河北 |
| 英文关键词:malignant tumor incidence mortality disease burden disability-adjusted life years Hebei |
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| 中文摘要: |
| 摘 要：［目的］ 分析2020年河北省肿瘤登记地区恶性肿瘤发病、死亡及疾病负担情况。［方法］ 收集整理2020年河北省肿瘤登记地区恶性肿瘤患者发病和死亡数据。计算分析恶性肿瘤发病率、死亡率、年龄别发病（死亡）率及标化发病（死亡）率，年龄标准化发病（死亡）率采用 2000 年全国标准人口构成和 Segi世界标准人口构成计算，根据世界卫生组织（WHO）推荐的Excel疾病负担计算模板计算分析伤残调整寿命年（disability-adjusted life years，DALY）等疾病负担指标。［结果］ 2020年河北省肿瘤登记地区恶性肿瘤粗发病率、中标率和世标率分别为229.36/10万、147.06/10万和143.74/10万，男性发病率高于女性，城市地区和农村地区粗发病率分别为230.26/10万和228.84/10万，年龄别发病率在80~84岁年龄组达到高峰。恶性肿瘤粗死亡率及其中标率和世标率分别为146.38/10万、85.33/10万和84.79/10万，男性死亡率高于女性，城市和农村地区死亡率分别为143.82/10万和147.84/10万，年龄别死亡率随年龄升高而逐渐上升，在85岁及以上年龄组达到峰值。2020年河北省肿瘤登记地区恶性肿瘤DALY为345 030人年，在45~59岁年龄段达到最大值；DALY率为15.00‰，70~79岁年龄段最高，其中肺癌疾病负担最为沉重，DALY为83 684人年，占全部恶性肿瘤的24.25%，其次为胃癌、肝癌、女性乳腺癌和结直肠癌。城市及农村地区DALY分别为122 062人年和222 993人年，DALY率变化趋势基本相同。［结论］ 河北省恶性肿瘤疾病负担较为沉重，防控形势严峻，今后防治工作应将城市男性及中老年人群作为重点防治人群，减轻恶性肿瘤对居民健康的影响。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the incidence， mortality and disease burden of malignant tumors in the cancer registration areas of Hebei Province in 2020. ［Methods］ The incidence and mortality data of cancer in 2020 were collected from the cancer registries of Hebei Province， and the quality of data was evaluated. The crude incidence (mortality) rate， age-specific incidence (mortality) rates and age-standardized incidence (mortality) rates by Chinese standard population (ASIRC/ASMRC) and world standard population (ASIRW/ASMRW) were calculated and analyzed. The disability-adjusted life years (DALY) were calculated and analyzed according to the Excel disease burden calculation template recommended by the World Health Organization (WHO). ［Results］ In 2020， the crude incidence rate， ASIRC， ASIRW of malignant tumors in the cancer registration areas of Hebei Province were 229.36/105， 147.06/105 and 143.74/105， respectively. The incidence rate in men was higher than that in women. The incidence rates in urban and rural areas were 230.26/105 and 228.84/105， and the age-standardized incidence rates reached a peak in the age group of 80~84 years old. The crude mortality rate， ASMRC， ASMRW were 146.38/105， 85.33/105 and 84.79/105， respectively. The mortality rate in men was higher than that in women. The age-standardized mortality rate rose with age， reaching a peak in the age group of 85+ years old， and the crude mortality rates in urban and rural areas were 143.82/105 and 147.84/105， respectively. The DALY of malignant tumors in the cancer registration areas of Hebei Province were 345 030 person-years， reaching a maximum in the age group of 45~59 years old， with a DALY rate of 15.00/103， and the highest in the age group of 70~79 years old. Lung cancer had the heaviest disease burden， with DALY of 83 684 person-years， accounting for 24.25% of all malignant tumors， followed by stomach， liver， female breast， and colorectal cancers. The DALY in urban and rural areas were 122 062 and 222 993 person-years， respectively， and the trends in DALY rates were basically stable. ［Conclusion］ The disease burden of malignant tumors in Hebei Province is relatively heavy， cancer prevention and control should be further strengthened and focused on urban men and the elderly to reduce disease burden of malignant tumors in the future. |
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