| 石玥昕,商 娜,乔丽颖,等.2016—2018年内蒙古自治区肝癌高危人群筛查依从性及影响因素分析[J].中国肿瘤,2025,34(1):58-66. |
| 2016—2018年内蒙古自治区肝癌高危人群筛查依从性及影响因素分析 |
| Compliance of Liver Cancer Screening and Related Influencing Factors in Inner Mongolia from 2016 to 2018 |
| 投稿时间：2024-01-06 |
| DOI：10.11735/j.issn.1004-0242.2025.01.A010 |
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| 中文关键词: 肝癌 筛查 依从性 内蒙古 |
| 英文关键词:liver cancer screening compliance Inner Mongolia |
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| 摘要点击次数: 100 |
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| 中文摘要: |
| 摘 要：［目的］ 分析2016—2018年内蒙古自治区肝癌高危人群筛查依从性及影响因素。［方法］ 选取内蒙古地区40~74岁常住居民进行癌症危险因素问卷调查和肝癌高危因素风险评估，对评估出的肝癌高危人群进行血清甲胎蛋白检测及腹部超声检查，计算肝癌高危人群筛查依从性及阳性病变检出率。采用χ2检验比较不同特征人群肝癌筛查率差异，采用多因素Logistic回归模型分析肝癌筛查率相关影响因素。［结果］ 2016—2018年共70 109位居民完成问卷调查和肝癌高危风险评估，评估出肝癌高危人群11 211人，肝癌高危率为15.99%。共4 998人参加了肝癌筛查，肝癌筛查依从性44.58%。临床筛查共检出AFP阳性125例（2.50%）、肝占位11例（0.22%）、肝硬化6例（0.12%）、脂肪肝2 303例（46.08%）。多因素Logistic回归分析结果显示，女性、45～49岁和50~54岁年龄组、蒙古族和其他少数民族、每周蔬菜摄入量＜2.5 kg和≥2.5 kg、饮食油脂较高、目前吸烟和曾经吸烟、目前饮酒、曾经饮茶、精神创伤史、近年承受巨大压力、患有肝胆系统疾病和慢性乙型肝炎的肝癌高危人群更易参加肝癌临床筛查（P均<0.05）。［结论］ 2016—2018年内蒙古自治区肝癌高危人群筛查依从性较低但阳性检出率较高，应进一步完善筛查机制，提高肝癌高危人群筛查依从性，提高筛查效果及防控水平。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the compliance of liver cancer clinical screening and related influencing factors in Inner Mongolia from 2016 to 2018. ［Methods］ The liver cancer screening program was conducted among permanent residents aged 40～74 years old in Inner Mongolia from 2016 to 2018. The risk factor assessment questionnaire was used for primary screening， and the identified high-risk subjects of liver cancer were subject to undergo clinical screening including ultrasound examination and serum AFP test. The clinical screening rate of high-risk subjects and detection rate were calculated and compared among different groups. Multivariate Logistic regression model was used to analyze influencing factors related to the clinical screening rate of liver cancer. ［Results］ A total of 70 109 residents completed questionnaires risk assessments from 2016 to 2018， and 11 211 subjects were identified as high-risk of liver cancer with the high-risk rate of 15.99%. Among 11 211 high-risk subjects， 4 998 underwent clinical screening with a screening rate of 44.58%. There were 125 cases of AFP positive (2.50%)， 11 cases of occupying lesions in the liver (0.22%)， 6 cases of cirrhosis (0.12%)， and 2 303 cases of fatty liver (46.08%). Multivariate Logistic regression analysis showed that female， age of 45～54 years old ， Mongolians and other ethnic minorities， individuals with vegetables intake <2.5 kg/week and ≥2.5 kg/week， high-fat diet， history of smoking， smoking， alcohol drinking， history of tea-drinking， history of psychological trauma and stress in recent years， diseases of hepatobiliary system， and chronic hepatitis B were more likely to participate in clinical screening (all P<0.05). ［Conclusion］ The screening compliance of high-risk population for liver cancer is low but the detection rate is high in Inner Mongolia from 2016 to 2018. The program mechanism should be improved to increase the liver cancer screening compliance. |
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