| 旦增索朗,次仁央金,德 吉,等.2015—2019年西藏拉萨市农村上消化道癌筛查结果分析[J].中国肿瘤,2025,34(1):52-57. |
| 2015—2019年西藏拉萨市农村上消化道癌筛查结果分析 |
| Analysis of Upper Gastrointestinal Cancer Screening Results in Rural Areas of Lhasa in Xizang from 2015 to 2019 |
| 投稿时间：2024-03-02 |
| DOI：10.11735/j.issn.1004-0242.2025.01.A009 |
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| 中文关键词: 上消化道癌 内镜检查 筛查 早诊早治 西藏 |
| 英文关键词:upper gastrointestinal cancer endoscopy screening early diagnosis and treatment Xizang |
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| 中文摘要: |
| 摘 要：［目的］ 分析2015—2019年西藏拉萨市农村上消化道癌早诊早治项目筛查结果。［方法］ 2015—2019年间，在西藏拉萨市3个区采用整群抽样方法，选取40~69岁居民进行上消化道内镜检查，所有病变的确诊均以病理学检查为依据。计算上消化道癌（包括食管癌与胃癌）各级别病变的检出率，采用χ2检验对不同区域、性别、年龄人群的检出率进行比较。［结果］ 共有1 399人完成胃镜检查，其中1 288人完成病理活检（92.07%）。经病理确诊，食管癌检出率为0.21%（3/1 399），均为进展期鳞癌；胃癌检出率为0.57%（8/1 399），其中早期胃癌2例；胃黏膜低级别上皮内瘤变检出率为0.64%（9/1 399）；胃黏膜高级别上皮内瘤变检出率为0.21%（3/1 399）。不同地区、性别及年龄组间上消化道癌检出率差异均无统计学意义（P均>0.05）。［结论］ 西藏拉萨市上消化道癌筛查检出率远低于全国平均水平，男性和老年人群在上消化道癌筛查中属于重点关注群体，需要提升该人群的筛查参与度，进而提高筛查效果。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the results of upper gastrointestinal cancer screening in rural areas of Lhasa from 2015 to 2019. ［Methods］ Upper gastrointestinal cancer screening program was conducted among residents aged 40～69 years old from 3 rural project sites in Lhasa selected by cluster sampling method from 2015 to 2019. The detected malignant tumors and precancerous lesions were treated and confirmed by pathological examination. The detection rate of esophagus and stomach cancer were calculated by region， sex and age and compared by χ2 test. ［Results］ A total of 1 399 people underwent gastroscopy， among whom 1 288 completed pathological biopsy (92.07%). Three cases of esophageal cancer were detected with a detection rate of 0.21% (3/1 399)， all of which were advanced squamous cell carcinoma. Eight cases of gastric cancer were detected with a detection rate of 0.57% (8/1 399)， and 2 cases were early gastric cancer. The detection rate of low-grade and high-grade epithelial neoplasia of gastric mucosa was 0.64% (9/1 399) and 0.21% (3/1 399)，respectively. There was no significant difference in the detection rate among different regions， sexes and age groups（all P>0.05). ［Conclusion］ The detection rate of upper gastrointestinal cancer in screening population in Lhasa is lower than the national average level. Men and the elderly are important target populations for upper gastrointestinal cancer screening，and increasing participation rates is necessary for more effective screening outcomes. |
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