| 薛 峰,费兴林,孙 晶,等.1991—2020年浙江省嘉善县结直肠癌生存分析[J].中国肿瘤,2025,34(1):32-36. |
| 1991—2020年浙江省嘉善县结直肠癌生存分析 |
| Survival Analysis of Colorectal Cancer in Jiashan County， Zhejiang Province from 1991 to 2020 |
| 投稿时间：2024-07-05 |
| DOI：10.11735/j.issn.1004-0242.2025.01.A006 |
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| 中文关键词: 结直肠癌 观察生存率 相对生存率 浙江 |
| 英文关键词:colorectal cancer observed survival rate relative survival rate Zhejiang |
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| 摘要点击次数: 89 |
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| 中文摘要: |
| 摘 要： ［目的］ 分析1991—2020年浙江省嘉善县结直肠癌患者的生存情况。［方法］ 收集浙江省嘉善县1991年1月1日至2020年12月31日期间新发的结直肠癌病例，随访日期截至2023年12月。以5年为1组，采用寿命表法和Ederer Ⅱ法分别计算观察生存率和相对生存率，相对生存标化采用国际癌症生存标准进行调整。采用Joinpoint回归模型计算平均年度变化百分比（average annual percentage change，AAPC），分析各类结直肠癌生存率在1991—2020年期间的变化趋势。［结果］ 1991—2020年浙江省嘉善县结直肠癌5年相对生存率从21.7%（1991—1995年）上升至73.4%（2016—2020年），并呈逐年递增趋势（AAPC=4.6%，P＜0.05）。5年相对生存率在男性和女性分别从1991—1995年的17.7%和30.0%上升至2016—2020年的72.7%和74.3%，女性增幅（AAPC=4.3%）高于男性（AAPC=3.9%）。各年龄组的结直肠癌5年相对生存率均呈逐年递增趋势，其中65~74岁年龄组的增幅最大（AAPC=4.9%）；除75岁及以上年龄组外，其余年龄组5年相对生存率变化趋势均有统计学意义（P均＜0.05）。［结论］ 1991—2020年浙江省嘉善县结直肠癌5年生存率逐年提高，其中女性5年生存率增幅高于男性，65~74岁年龄组增幅最大。应对重点人群进行早诊早治筛查，提高结直肠癌生存率。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the survival of colorectal cancer patients in Jiashan County of Zhejiang Province from 1991 to 2020. ［Methods］ The data of newly reported cases of colorectal cancer were collected in Jiashan County from January 1， 1991 to December 31， 2020， and patients were followed-up till December 2023. The observed survival rate (OSR) and relative survival rate (RSR) were calculated using the life table and Ederer Ⅱ method with 5-year intervals. Relative survival was adjusted using the International Cancer Survival Standards. The Joinpoint regression model was used to calculate the average annual percentage change (AAPC) to analyze the change trend of survival rate. ［Results］ The 5-year RSR of colorectal cancer increased from 21.7% during 1991 to 1995 to 73.4% during 2016 to 2020， showing an increasing trend (AAPC=4.6%， P<0.05)， for men it increased from 17.7% to 72.7% and for women it increased from 30.0% to 74.3%， with AAPCs of 3.9% and 4.3%， respectively (P<0.05). The 5-year RSR of colorectal cancer in all age groups showed an increasing trend (P<0.05 for all age groups， except for 75+)， and the highest increase was found in the age group of 65~74 years old(AAPC=4.9%). ［Conclusion］ From 1991 to 2020， the 5-year survival rate of colorectal cancer in Jiashan County showed a steady increase， for women and those aged 65~74 years old the increase was more significant. The cancer screening of high-risk groups should be focused on to improve colorectal cancer survival rate. |
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