杨志杰,王 璐,钱 云,等.2009—2019年江苏省肿瘤登记地区甲状腺癌发病趋势和年龄变化特征分析[J].中国肿瘤,2024,33(12):991-998.
2009—2019年江苏省肿瘤登记地区甲状腺癌发病趋势和年龄变化特征分析
Trends of Incidence and Diagnostic Age of Thyroid Cancer in Cancer Registration Areas of Jiangsu Province from 2009 to 2019
投稿时间:2024-04-22  
DOI:10.11735/j.issn.1004-0242.2024.12.A005
中文关键词:  甲状腺癌  发病  趋势  江苏
英文关键词:thyroid cancer  incidence  trend  Jiangsu
基金项目:南医大无锡医学中心-专病队列(WMCC202312);无锡市科技发展资金项目(K20231046);无锡市卫生健康委科普作品创作项目(P202314)
作者单位
杨志杰 无锡市疾病预防控制中心 
王 璐 无锡市疾病预防控制中心 
钱 云 无锡市疾病预防控制中心 
陈 海 无锡市疾病预防控制中心 
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中文摘要:
      摘 要:[目的] 分析2009—2019年江苏省肿瘤登记地区甲状腺癌发病趋势及年龄变化情况。[方法] 将2009—2019年登记数据连续完整,且各项质控指标均符合要求的16个登记处,作为江苏省恶性肿瘤流行趋势分析的样本数据源,收集ICD-10为C73的甲状腺癌数据。计算不同地区、分性别人群甲状腺癌的发病率、中标率、世标率、标化平均发病年龄、年均变化百分比(average annual percentage change,AAPC)及其95%置信区间(confidence interval,CI),年份与平均发病年龄的趋势变化用线性回归模型分析。[结果] 江苏省肿瘤登记地区男性2009年甲状腺癌发病率和中标率分别为1.25/10万和1.00/10万,2019年分别为7.32/10万和6.48/10万;女性2009年分别为3.64/10万和3.06/10万,2019年分别为24.91/10万和20.94/10万。2009—2019年江苏省肿瘤登记地区甲状腺癌发病率和中标率均呈上升趋势(发病率:AAPC=22.05%,95%CI:19.70%~24.45%;中标率:AAPC=22.55%,95%CI:20.06%~25.08%);标化平均发病年龄由2009年的46.27岁下降到2019年的43.03岁(β=-0.243,P<0.001)。[结论] 2009—2019年江苏省肿瘤登记地区甲状腺癌发病率呈上升趋势,标化平均发病年龄呈下降态势。
英文摘要:
      Abstract:[Purpose] To analyze the incidence trend and age at diagnosis of thyroid cancer in cancer registration areas of Jiangsu Province from 2009 to 2019. [Methods] The continuous and complete cancer data from 2009 to 2019 meeting quality control requirements were collected from 16 registries in Jiangsu Province. Thyroid cancer was coded as C73 according to ICD-10. The crude incidence rate, age-standardized incidence rate by Chinese standard population(ASIRC), the mean diagnostic age and adjusted mean diagnostic age of thyroid cancer were calculated by sex, age groups and regions. The trends of above indicators were analyzed and the average annual percentage change(AAPC) was calculated. [Results] The crude incidence rate and ASIRC of thyroid cancer for men in Jiangsu cancer registration areas in 2009 and 2019 were 1.25/105, 1.00/105 and 7.32/105, 6.48/105, respectively. For women those were 3.64/105, 3.06/105 and 24.91/105, 20.94/105, respectively. The AAPC of crude incidence rate and ASIRC of thyroid cancer from 2009 to 2019 were 22.05% (95%CI: 19.70%~24.45%) and 22.55% (95%CI: 20.06%~25.08%), respectively. The adjusted mean diagnostic age of thyroid cancer declined from 46.27 years old in 2009 to 43.03 years old in 2019 (β=-0.243, P<0.001). [Conclusion] The incidence rate of thyroid cancer showed an increasing trend in cancer registration areas of Jiangsu Province from 2009 to 2019, while the diagnostic age showed a downward trend during the same period.
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