| 李伟伟,董建梅,马昭君,等.2009—2019年江苏省肿瘤登记地区子宫体癌发病趋势及年龄变化分析[J].中国肿瘤,2024,33(12):977-982. |
| 2009—2019年江苏省肿瘤登记地区子宫体癌发病趋势及年龄变化分析 |
| Trends of Incidence and Age at Onset of Uterine Corpus Cancer in Jiangsu Cancer Registration Areas from 2009 to 2019 |
| 投稿时间：2024-04-28 |
| DOI：10.11735/j.issn.1004-0242.2024.12.A003 |
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| 中文关键词: 子宫体癌 发病 年龄 趋势 江苏 |
| 英文关键词:uterine corpus cancer incidence age trend Jiangsu |
| 基金项目:江苏省卫生计生委预防医学科研课题（Y2015030） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2009—2019年江苏省肿瘤登记地区子宫体癌发病趋势及年龄变化情况。［方法］ 汇总2009—2019年江苏省肿瘤登记数据连续完整、质控达标的16个登记地区资料，计算各年份子宫体癌发病率、中国人口标化发病率（中标率）、平均发病年龄、标化平均发病年龄和标化年龄发病构成比等指标。采用Joinpoint回归模型分析2009—2019年子宫体癌发病率的平均年变化百分比（average annual percentage change，AAPC），利用线性回归模型分析标化平均发病年龄与年份之间的相关性，比较2009和2019年标化年龄发病构成比变化情况。［结果］ 2009—2019年江苏省肿瘤登记地区合计及农村地区的子宫体癌中标发病率均呈明显上升趋势，其AAPC分别为1.78%和2.38%（P均<0.05），但城市地区中标发病率变化趋势不明显（AAPC=1.30%，P>0.05）。子宫体癌的平均发病年龄由2009年的56.48岁增长至2019年的58.26岁，年均增长0.173岁（P=0.001）；但调整人口构成标化后，标化平均发病年龄无明显趋势变化。［结论］ 2009—2019年江苏省肿瘤登记地区子宫体癌的发病水平呈现明显上升趋势，尤其是50~59岁年龄组人群。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the trends of incidence and age at onset of uterine corpus cancer in Jiangsu cancer registration areas from 2009 to 2019. ［Methods］ The continuous monitoring data of uterine corpus cancer from 2009 to 2019 were collected from 16 cancer registries in Jiangsu Province. The crude incidence rate， the age-standardized incidence rate by Chinese standard population(ASIRC)， crude and adjusted mean age， and standardized age-specific incidence composition were calculated. The average annual percentage change(AAPC) were analyzed by the Joinpoint regression model. The linear regression model was used to analyze the relationship between mean age at onset and year. The standardized age-specific incidence composition in 2009 and 2019 were compared. ［Results］ The ASIRC of uterine corpus cancer in all registration areas and in rural areas of Jiangsu Province showed upward trends with AAPC of 1.78% and 2.38%， respectively (P<0.05)， but not showed in the urban areas (AAPC=1.30%， P>0.05). The crude mean age at onset increased from 56.48 years old in 2009 to 58.26 years old in 2019 with an average annual growth of 0.173 years old(P=0.001). After the population structure standardized， the trends disappeared in all registration areas. ［Conclusion］ From 2009 to 2019， the standardized incidence rates of uterine corpus cancer were on rise in Jiangsu cancer registration areas， especially in the age group of 50 to 59 years old. |
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