| 马珠媛,闫 纳,丁高恒,等.2019年甘肃省肿瘤登记地区甲状腺癌流行特征及2010—2019年变化趋势分析[J].中国肿瘤,2024,33(11):922-929. |
| 2019年甘肃省肿瘤登记地区甲状腺癌流行特征及2010—2019年变化趋势分析 |
| Epidemic Characteristics of Thyroid Cancer in Gansu Cancer Registration Areas in 2019 and Trends from 2010 to 2019 |
| 投稿时间：2023-12-30 |
| DOI：10.11735/j.issn.1004-0242.2024.11.A007 |
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| 中文关键词: 甲状腺癌 发病率 死亡率 趋势 甘肃 |
| 英文关键词:thyroid cancer incidence mortality trend Gansu |
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| 中文摘要: |
| 摘 要： ［目的］ 分析2019年甘肃省肿瘤登记地区甲状腺癌发病与死亡情况及2010—2019年甲状腺癌趋势变化情况。［方法］ 按照国家癌症中心制定的数据质量审核评价标准，对甘肃省符合质控要求的23个肿瘤登记处上报的甲状腺癌发病（死亡）率、标化发病（死亡）率、0~74岁累积率等指标按照性别、年龄、地区分别进行计算。利用Joinpoint软件计算年度变化百分比（annual percentage change，APC）和平均年度变化百分比（average annual percentage change，AAPC），分析2010—2019年变化趋势。［结果］ 2019年甘肃省肿瘤登记地区甲状腺癌粗发病率为6.89/10万，中标率为5.50/10万，世标率为5.33/10万，0~74岁累积率为0.48%。甲状腺癌粗死亡率为0.42/10万，中标率为0.27/10万，世标率为0.31/10万，0~74岁累积率为0.03%。发病率和死亡率分别在30岁和55岁开始逐渐上升，高峰分别集中在45~49岁和60~64岁年龄组。兰州市城关区中标发病率最高，古浪县中标死亡率最高。2010—2019年甘肃省肿瘤登记地区甲状腺癌中标发病率的AAPC为17.12%（95%CI：7.52%~30.42%），呈明显上升趋势（P<0.05）；甲状腺癌中标死亡率的AAPC为-3.64%（95%CI： -15.67%~10.10%），趋势变化无统计学意义（P>0.05）。［结论］ 甘肃省甲状腺癌整体发病水平呈上升趋势，应加强对高危人群的疾病预防。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of thyroid cancer in Gansu cancer registration areas in 2019 and the trends from 2010 to 2019. ［Methods］ The data of thyroid cancer from 2010 to 2019 were collected from 23 cancer registries in Gansu Province and the data quality was evaluated. The crude incidence/mortality rates， age-standardized incidence/mortality rates by Chinese standard population (ASIRC，ASMRC) and world standard population (ASIRW，ASMRW) and cumulative rate (0~74 years old) were calculated. The annual percentage change (APC) and average annual percentage change (AAPC) were calculated with Joinpoint software to analyze the trends of the incidence and mortality from 2010 to 2019. ［Results］ In 2019， the crude incidence of thyroid cancer was 6.89/105， the ASIRC was 5.50/105， the ASIRW was 5.33/105 and the cumulative rate (0~74 years old) was 0.48% in 2019. The crude mortality rate of thyroid cancer was 0.42/105， ASMRC was 0.27/105， ASMRW was 0.31/105， cumulative rate (0~74 years old) was 0.03%. Incidence and mortality rates gradually increasing at age 30 and 55， respectively， reaching the peaks in the 45~49 and 60~64 age groups， respectively. Chengguan District of Lanzhou City had the highest incidence rate， and Gulang County had the highest mortality rate. From 2010 to 2019， the AAPC of ASIRC of thyroid cancer was 17.12% (95%CI：7.52%~30.42%， P＜0.05) showing an upwards trend； while that of ASMRC was -3.64% (95%CI：-15.67%~10.10%， P>0.05) showing a downward trend， but the change was not statistically significant. ［Conclusion］ The overall incidence of thyroid cancer in Gansu cancer registration areas is on the rise， and the prevention of high-risk groups should be strengthened. |
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