| 王 丹,邹雪平,成姝雯,等.2015—2019年四川省肿瘤登记地区前列腺癌流行特征及早死疾病负担趋势分析[J].中国肿瘤,2024,33(9):709-715. |
| 2015—2019年四川省肿瘤登记地区前列腺癌流行特征及早死疾病负担趋势分析 |
| Analysis on the Trend of Epidemiological Characteristics of Prostate Cancer and Disease Burden of Early Death in Sichuan Cancer Registration Areas from 2015 to 2019 |
| 投稿时间：2024-01-22 |
| DOI：10.11735/j.issn.1004-0242.2024.09.A002 |
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| 中文关键词: 前列腺癌 发病率 死亡率 趋势分析 四川 |
| 英文关键词:prostate cancer incidence mortality trend analyses Sichuan |
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| 摘要点击次数: 163 |
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| 中文摘要: |
| 摘 要：［目的］ 分析2015—2019年四川省肿瘤登记地区前列腺癌发病和死亡的流行特征及其导致的早死情况的趋势变化。［方法］ 利用四川省肿瘤登记地区2015—2019年收集的前列腺癌发病与死亡数据，计算分城乡、年龄组前列腺癌发病和死亡的粗率、中国人口标化率（中标率）以及早死寿命损失年（years of life lost，YLL）和YLL 率等指标，变化趋势采用平均年度变化百分比（average annual percentage change，AAPC）进行分析。［结果］ 2015—2019年四川省肿瘤登记地区前列腺癌粗发病率和中标率分别为9.67/10万和5.07/10万，粗死亡率和中标率分别为4.44/10万和2.24/10万；前列腺癌中标发病率和死亡率均是城市高于农村地区，但农村地区的增长速度快于城市。前列腺癌发病和死亡在60岁之后快速上升，在85岁及以上年龄组达到顶峰。2015—2019年四川省肿瘤登记地区前列腺癌粗发病率、粗死亡率和中标发病率均呈上升趋势，AAPC分别为13.63%、8.53%和7.62%（P均<0.05）；农村地区前列腺癌的YLL率呈逐年上升趋势，AAPC为9.00%（P<0.05），总人群和城市地区的YLL率的趋势变化均无统计学意义（P均>0.05）。［结论］ 四川省肿瘤登记地区前列腺癌的发病和死亡水平呈上升趋势，城市地区前列腺癌发病率和死亡率高于农村，但农村地区的增长速度快于城市，农村地区的老年男性是前列腺癌应重点关注的人群，应开展早期筛查和干预。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends of incidence， mortality and disease burden of prostate cancer in Sichuan cancer registration areas from 2015 to 2019. ［Methods］ Prostate cancer incidence and mortality data from 2015 to 2019 were collected from Sichuan cancer registration areas. The crude rate and age-standardized rate of prostate cancer in urban and rural areas and different age groups， years of life lost (YLL) and YLL rate were calculated. Average annual percentage change (AAPC) was used to analyze the trend. ［Results］ In Sichuan cancer registration areas from 2015 to 2019， the crude incidence and age-standardized incidence rate by Chinese standard population(ASIRC) of prostate cancer were 9.67/105 and 5.07/105， respectively. Crude mortality and age-standardize mortality rate by Chinese standard population (ASMRC) were 4.44/105 and 2.24/105， respectively. The ASIRC and ASMRC of prostate cancer were higher in urban areas than those in rural areas， but the rate of increase in rural areas was faster than that in urban areas. Prostate cancer incidence and mortality rose rapidly after age group of 60 years old， peaking in the age group of 85 years old and above. From 2015 to 2019， the crude incidence， crude mortality and ASIRC of prostate cancer were increasing， with AAPC of 13.63%， 8.53% and 7.62%， respectively (all P<0.05). The YLL rate of prostate cancer in rural areas of Sichuan cancer registration areas increased with an AAPC of 9.00% (P<0.05)， the trend of YLL rate in the general population and urban areas was not statistically significant (both P>0.05). ［Conclusion］ The incidence and mortality of prostate cancer are on the rise in Sichuan cancer registration areas， particularly in urban areas. The elderly men in rural areas should be the focus of prostate cancer prevention and control. |
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