| 汪 萍,钟节鸣,李 娜,等.1990—2019年浙江省肺癌疾病负担和危险因素变化趋势的研究[J].中国肿瘤,2024,33(7):565-572. |
| 1990—2019年浙江省肺癌疾病负担和危险因素变化趋势的研究 |
| Trends of Disease Burden and Risk Factors of Lung Cancer in Zhejiang Province from 1990 to 2019 |
| 投稿时间：2023-12-08 |
| DOI：10.11735/j.issn.1004-0242.2024.07.A008 |
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| 中文关键词: 肺癌 疾病负担 伤残调整寿命年 危险因素 浙江 |
| 英文关键词:lung cancer disease burden disability-adjusted life years risk factor Zhejiang |
| 基金项目:STS区域重点项目（KFJ-STS-QYZD-2021-08-001） |
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| 中文摘要: |
| 摘 要：［目的］ 分析1990—2019年浙江省肺癌疾病负担和危险因素变化趋势。［方法］ 利用2019年全球疾病负担研究结果，分析1990—2019年浙江省居民肺癌的早死损失寿命年（YLL）、伤残损失健康寿命年（YLD）和伤残调整寿命年（DALY）的变化趋势及浙江省肺癌主要危险因素的变化，同时与全国、全球及全球不同社会人口学指数（SDI）地区比较。［结果］ 1990—2019年浙江省肺癌所致标化YLL率和DALY率总体呈现下降趋势，平均年度变化百分比分别为 -0.25%、-0.17%，标化YLD 率平均年度变化百分比为0.96%。2019年浙江省肺癌所致标化 YLL率、YLD 率和 DALY 率分别为599.68/10 万、7.80/10 万和607.49/10 万，低于同期全国平均水平但高于全球水平和全球不同SDI地区。YLL率、YLD 率和 DALY 率在70岁及以上年龄组人群最高，15~49 岁年龄组最低，男性远高于女性。2019 年浙江省肺癌的主要危险因素为吸烟、环境颗粒物污染、二手烟暴露、空腹高血糖和职业接触二氧化硅，相比较于1990年，空腹高血糖对浙江省肺癌疾病负担的危害程度排名有所提升。［结论］ 浙江省肺癌所致YLL率和DALY率在1990—2019年间总体呈现下降趋势，同时也存在高年龄组及男性的疾病负担较重等问题；前16位主要归因危险因素恒定不变，但顺位有不同程度的变化。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the change trends of disease burden and risk factors of lung cancer in Zhejiang Province from 1990 to 2019. ［Methods］ Based on the data of the 2019 Global Burden of Disease Study， the changing trends of years of life lost (YLL)， years lived with disability (YLD) and disability-adjusted life years (DALY)， and the major risk factors of lung cancer in Zhejiang Province from 1990 to 2019 were analyzed. The indicators of disease burden were compared with those of China national level， global level and global regions with different socio-demographic index (SDI) . ［Results］ From 1990 to 2019， the standardized YLL rate and DALY rate caused by lung cancer in Zhejiang Province showed a decreasing trend， the average annual percentage change (AAPC) was -0.25% and -0.17%， respectively， and the AAPC of standardized YLD rate was 0.96%. In 2019， the rates of age-standardized YLL， age-standardized YLD and age-standardized DALY caused by lung cancer in Zhejiang Province were 599.68/105， 7.80/105 and 607.49/105， respectively， which were lower than those of China national level but higher than those of the global level and different SDI regions in the world. The highest YLL rate， YLD rate and DALY rate were found in the age group of 70+ years old and the lowest in the age group of 15~49 years old. The YLL rate， YLD rate and DALY rate in male were significantly higher than that in female. In 2019， the main risk factors of lung cancer in Zhejiang Province were smoking， environmental particulate pollution， exposure to second-hand smoke， fasting hyperglycemia and occupational exposure to silica. Compared with 1990， the ranking of the harm degree of fasting hyperglycemia was increased in 2019. ［Conclusion］ The YLL and DALY rates of lung cancer in Zhejiang Province show an overall downward trend from 1990 to 2019， however， the disease burden for elderly and males are still heavy. The top 16 main attributable risk factors remain constant， but their ranks show somewhat changes. |
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