| 袁芝佩,王 丹,成姝雯,等.2019年四川省肿瘤登记地区恶性肿瘤发病与死亡及2015—2019年变化趋势分析[J].中国肿瘤,2024,33(7):515-522. |
| 2019年四川省肿瘤登记地区恶性肿瘤发病与死亡及2015—2019年变化趋势分析 |
| Cancer Incidence and Mortality in Sichuan Cancer Registration Areas in 2019 and Its Trend from 2015 to 2019 |
| 投稿时间：2023-12-13 |
| DOI：10.11735/j.issn.1004-0242.2024.07.A001 |
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| 中文关键词: 恶性肿瘤 发病率 死亡率 四川 |
| 英文关键词:cancer incidence mortality Sichuan |
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| 中文摘要: |
| 摘 要：［目的］ 分析2019年四川省肿瘤登记地区恶性肿瘤发病和死亡情况及2015—2019年变化趋势。［方法］ 分析2019年收集到质量合格的121个肿瘤登记处的恶性肿瘤发病与死亡数据，分别计算不同性别、年龄、城乡的粗发病/死亡率、中国人口标准化率（简称中标率）、世界人口标准化率（简称世标率）、 0～74岁累积率和前10位恶性肿瘤发病/死亡顺位等指标。利用Joinpoint 软件进行回归分析，计算2015—2019年恶性肿瘤发病与死亡的年度变化百分比（annual percentage change，APC）。［结果］ 2019年四川省肿瘤登记地区恶性肿瘤粗发病率为276.99/10万，中标发病率为 156.72/10万，世标发病率为154.11/10万，累积率( 0～74岁) 为17.87%。40岁以上人群恶性肿瘤发病水平快速上升，至80～84岁年龄组达到最高值。恶性肿瘤发病前5位依次为肺癌、肝癌、结直肠癌、女性乳腺癌、食管癌。2019年四川省肿瘤登记地区恶性肿瘤粗死亡率为185.09/10万，中标死亡率为97.18/10万，世标死亡率为96.83/10万，累积率( 0～74岁) 为11.16%。40岁以上人群死亡水平快速上升，至85岁及以上组达到最高值。恶性肿瘤死亡前5位依次为肺癌、肝癌、食管癌、胃癌、结直肠癌。2015—2019年四川省肿瘤登记地区恶性肿瘤中标发病率呈下降趋势，平均每年下降1.93%，趋势变化有统计学意义（P＜0.05）。［结论］ 四川省恶性肿瘤发病率略低于全国平均水平，但疾病负担仍然较重；肺癌、肝癌、结直肠癌、女性乳腺癌和食管癌是需要关注的重点癌种，50岁以上人群是恶性肿瘤高发人群，应针对重点癌种和人群开展综合防治工作。 |
| 英文摘要: |
| ［Purpose］ To analyse cancer incidence and mortality in Sichuan cancer registration areas in 2019 and its trend from 2015 to 2019. ［Methods］ Cancer data collected from 121 cancer regi-stries in 2019 were analyzed， including incidence/mortality， age-standardized rates by Chinese standard population (ASIRC， ASMRC) and world standard population (ASIRW， ASMRW)， cumulative rate of 0 to 74 years old and top 10 of incidence/mortality. The annual percentage change (APC) of cancer incidence and mortality in Sichuan cancer registration areas from 2015 to 2019 were calculated using Joinpoint Regression Program software. ［Results］ In 2019， the incidence of cancer in Sichuan cancer registration areas was 276.99/105， the ASIRC and ASIRW were 156.72/105 and 154.11/105， respectively. The cumulative rate of 0 to 74 years old was 17.87%. The incidence increased rapidly in people over 40 years old， reaching the highest value at the age group of 80 to 84 years old. The top 5 cancer incidence were lung cancer， liver cancer， colorectal cancer， female breast cancer and esophageal cancer. The mortality rate was 185.09/105， the ASMRC was 97.18/105， the ASMRW was 96.83/105， and the cumulative rate of 0 to 74 years old was 11.16%. The mortality increased rapidly in people over 40 years old， reaching the highest value at the age group of 85 and above years old. The top 5 cancer mortality were lung cancer， liver cancer， esophageal cancer， stomach cancer and colorectal cancer. From 2015 to 2019， ASIRC in Sichuan cancer registration areas showed a decreasing trend， with an average annual decrease of 1.93%， and the trend change was statistically significant (P<0.05). ［Conclusion］ The incidence of cancers in Sichuan is slightly lower than the national average level， but the disease burden is still relatively heavy. Lung cancer， liver cancer， colorectal cancer， female breast cancer and esophageal cancer are the major types of cancer in the province， and people over 50 years old are the groups with a high incidence of cancer， and comprehensive prevention and control should be carried out according to the key major and groups of cancer. |
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