| 佟陈昀颢,张水生,张韶凯,等.影像学检查对胰腺癌的鉴别诊断价值——全国多中心回顾性研究[J].中国肿瘤,2024,33(6):508-514. |
| 影像学检查对胰腺癌的鉴别诊断价值——全国多中心回顾性研究 |
| Differential Diagnostic Value of Imaging Tests for Pancreatic Cancer： A National Multicenter Retrospective Study |
| 投稿时间：2023-12-11 |
| DOI：10.11735/j.issn.1004-0242.2024.06.A013 |
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| 中文关键词: 影像学技术 胰腺癌 鉴别诊断效能 ROC曲线 |
| 英文关键词:imaging techniques pancreatic cancer differential diagnosis efficacy ROC curve |
| 基金项目:中国医学科学院肿瘤医院院级项目（NCC201710003） |
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| 中文摘要: |
| 摘 要：［目的］ 评价不同影像学检查对中国胰腺癌患者的鉴别诊断价值。［方法］ 收集全国七大区14家医院2005—2014年收治的首诊为胰腺肿瘤的患者病历，对其影像学检查资料进行分析，比较常用影像学技术单独检测的灵敏度、特异度、检出率及准确率，通过受试者工作特征（ROC）曲线分析影像学技术联合检测的鉴别诊断效能。［结果］ 共3 537例患者纳入研究。对于胰腺肿瘤性质的鉴别，在单独检测中，磁共振常规序列检查检出率、准确率、灵敏度最高，CT检查仅次于磁共振常规序列检查，经腹超声检查特异度最高。在联合检测中，CT与磁共振常规序列串联试验具有最高AUC值及约登指数，且均高于单独检测。［结论］ CT与磁共振常规序列检查能够有效检测出胰腺部位肿瘤，其串联试验对胰腺癌的鉴别诊断可提供良好的灵敏度、特异度，有较高的鉴别诊断价值，可为临床诊断提供一定参考。 |
| 英文摘要: |
| Abstract： ［Purpose］ To evaluate the value of various imaging techniques for differential diagnosis of pancreatic cancer. ［Methods］ The medical records of patients firstly diagnosed with pancreatic tumors were collected from 14 hospitals in 7 geographical regions of China from 2005 to 2014. Imaging data from these cases were analyzed. The sensitivity， specificity， detection rate， and accuracy of commonly used imaging techniques alone or in combination were compared and analyzed by the receiver operating characteristic(ROC) curve. ［Results］ A total of 3 537 patients were included in the final study. Among the commonly used imaging techniques， MRI had the highest detection rate， accuracy and sensitivity for pancreatic cancer， followed by CT examination； while transabdominal ultrasonography had the highest specificity. The combination of CT and MRI had the highest AUC value and Youden’s index for diagnosis of pancreatic cancer. ［Conclusion］ CT and MRI examinations can effectively detect tumors in the pancreatic area， and the combination of two examinations can provide good sensitivity and specificity for the differential diagnosis of pancreatic cancer. |
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