| 张 倩,陶秀丽,吴 宁.18F-FDG PET/CT在非小细胞肺癌免疫治疗疗效和预后评估中的研究进展[J].中国肿瘤,2024,33(3):247-253. |
| 18F-FDG PET/CT在非小细胞肺癌免疫治疗疗效和预后评估中的研究进展 |
| Advances of 18F-FDG PET/CT in Immunotherapy Response Assessment and Outcome Prediction for Non-Small Cell Lung Cancer Patients |
| 投稿时间：2023-06-26 |
| DOI：10.11735/j.issn.1004-0242.2024.03.A012 |
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| 中文关键词: 非小细胞肺癌 18F-FDG 正电子发射断层显像术 体层摄影术 X射线计算机 免疫治疗 |
| 英文关键词:non-small cell lung cancer 18F-FDG positron-emission tomography tomography, X-ray computer immunotherapy |
| 基金项目:国家自然科学基金青年科学基金项目（82001870） |
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| 中文摘要: |
| 摘 要：免疫治疗显著改善了晚期非小细胞肺癌（non-small cell lung cancer，NSCLC）患者的生存，但至今仍缺乏有效的生物标志物预测免疫治疗的疗效和预后。18-氟-2-脱氧-D-葡萄糖（18-fluoro-2-deoxy-D-glucose，18F-FDG）PET/CT作为一种无创的功能成像，能够表征全身肿瘤的糖代谢水平，在肿瘤免疫治疗的临床应用中展现出巨大潜力。全文就18F-FDG PET/CT在NSCLC免疫治疗疗效和预后评估中的研究进展进行综述。 |
| 英文摘要: |
| Abstract： Immunotherapy has significantly improved the survival of patients with advanced non-small cell lung cancer (NSCLC). However, there have not been reliable biomarkers to assess the efficacy and predict the outcome of immunotherapy. As a non-invasive functional imaging, 18-fluoro-2-deoxy-D-glucose (18F-FDG) PET/CT reflects glucose metabolism of tumors throughout the body, and has shown potential in clinical applications of immunotherapy. This paper reviews the progress of 18F-FDG PET/CT in immunotherapy efficacy assessment and outcome prediction for NSCLC patients |
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