| 陈海珍,徐 红,吉 光,等.2007—2017年江苏省南通市肿瘤医院乳腺癌住院患者生存率分析[J].中国肿瘤,2023,32(11):820-826. |
| 2007—2017年江苏省南通市肿瘤医院乳腺癌住院患者生存率分析 |
| Analysis of Survival Among Breast Cancer Inpatients in Nantong Tumor Hospital from 2007 to 2017 |
| 投稿时间：2023-09-02 |
| DOI：10.11735/j.issn.1004-0242.2023.11.A003 |
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| 中文关键词: 乳腺癌 肿瘤登记 随访 生存率 江苏 |
| 英文关键词:breast cancer cancer registration follow-up survival Jiangsu |
| 基金项目:南通市2022年度人口发展研究课题（20220914） |
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| 中文摘要: |
| 摘 要：［目的］ 对2007—2017年南通市肿瘤医院乳腺癌住院病例进行生存率分析。［方法］ 采用以医院为基础的肿瘤随访结合现场以人群为基础的肿瘤随访方法，随访截止于2020年12月31日。以寿命表法计算观察生存率（OSR），用SPSS 22.0软件进行统计分析并绘制曲线图，采用Wilcoxon统计量Gehan值作生存率比较。［结果］ 2007—2017年登记乳腺癌住院病例3 315例，经随访获得癌症生存结局3 291例（随访成功率为99.28%），其中男性31例（0.94%），女性3 260例（99.06%）。首次入院时平均年龄为（53.44±10.88）岁；以35～59岁为最多见(68.52%)，其次为60~79岁(26.86%)。每例患者平均住院（5.66±5.40）次。男性乳腺癌患者1、3、5及10年OSR分别为83.87%、74.19%、63.21%及19.39%；女性患者则分别为91.66%、79.02%、73.14%及63.37%，差异无统计学意义（P=0.078）。15～34岁、35～59岁、60～79岁及80～99岁各年龄组5年OSR分别为73.74%、75.71%、67.03%及56.80%（P<0.001）。2007—2012年及2013—2017年两个时期的5年OSR分别为69.42%及76.10%（P<0.001）。乳腺癌生存率存在地区差异。TNM分期显示Ⅰ期、Ⅱ期、Ⅲ期及Ⅳ期病例的5年OSR分别为94.30%、92.58%、71.52%及31.37%（P<0.001）。［结论］ 2007—2017年乳腺癌患者以中老年女性为主，青壮年女性乳腺癌的生存率较高；分期为Ⅰ期、Ⅱ期的早期乳腺癌患者预后较好。应该加强乳腺癌的综合防治能力。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the survival of breast cancer inpatients at Nantong Tumor Hospital from 2007 to 2017. ［Methods］ Patients with breast cancer who were residents in Nantong area and admitted in Nantong Tumor Hospital from 2007 to 2017 were followed up until December 31， 2020. The observed survival rate(OSR) was calculated using the life table method， and analyzed using SPSS 22.0 software. The Wilcoxon statistic(Gehan value) was employed for survival comparison. ［Results］ A total of 3 315 registered breast cancer inpatients between 2007 and 2017 were identified， and the outcomes were followed in 3 291 cases including 31 males (0.94%) and 3 260 females(99.06%)， with a follow-up rate of 99.28%. The ages of patients upon initial admission were (53.44±10.88) years old. The age group with the highest incidence was 35～59 years old (68.52%)， followed by 60~79 years old (26.86%). The average number of hospital admission was 5.66±5.40 times. The 1-， 3-， 5-， and 10-year OSRs for male breast cancer patients were 83.87%， 74.19%， 63.21%， and 19.39%， respectively； and those for female patients were 91.66%， 79.02%， 73.14%， and 63.37%， respectively (P=0.078). The 5-year OSR for the age groups of 15~34， 35~59， 60~79， and 80~99 years old were 73.74%， 75.71%， 67.03%， and 56.80%， respectively (P<0.001). The 5-year OSR for the periods 2007—2012 and 2013—2017 was 69.42% and 76.10%， respectively (P<0.001). There were regional variations in breast cancer survival. The 5-year OSRs of stages Ⅰ， Ⅱ， Ⅲ， and Ⅳ breast cancer were 94.30%， 92.58%， 71.52%， and 31.37%， respectively (P<0.001). ［Conclusion］ The study indicates that breast cancer primarily affected middle-aged and elderly females， with higher survival among younger female patients and poorer survival among those aged 80 and above； early-stage patients (stage Ⅰ and Ⅱ) exhibit better prognosis compared to late-stage patients (stage Ⅳ). |
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