| 朱永敬,罗鹏飞,孟 娜,等.2007—2021年江苏省淮河流域癌症早诊早治项目胃癌筛查结果分析[J].中国肿瘤,2023,32(8):596-602. |
| 2007—2021年江苏省淮河流域癌症早诊早治项目胃癌筛查结果分析 |
| Analysis of Screening Results of Early Diagnosis and Treatment of Gastric Cancer in the Huaihe River Basin of Jiangsu Province from 2007 to 2021 |
| 投稿时间：2023-05-13 |
| DOI：10.11735/j.issn.1004-0242.2023.08.A005 |
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| 中文关键词: 胃癌 筛查 淮河流域 江苏 |
| 英文关键词:gastric cancer screening Huaihe River basin Jiangsu |
| 基金项目:中国消化道早癌医师共同成长计划科研项目(GTCZ-2020-JS-32-0002) |
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| 中文摘要: |
| 摘 要：［目的］ 分析2007—2021年江苏省淮河流域癌症早诊早治项目地区的胃癌高危人群内镜筛查结果。［方法］ 通过整群抽样方法，抽取项目地区40~69岁常住居民进行胃癌风险评估，对评估为高危的个体行病理活检。采用χ2检验分析不同组间高危率、筛查率和检出率的差异；采用趋势χ2检验分析各年间高危率、筛查率和检出率的变化趋势。 ［结果］ 2007—2021年，参与问卷调查131 340人，共评估出高危对象78 191人，高危率为59.53%，研究人群的高危率随年龄的增长呈现上升趋势（P<0.01）。高危人群中共25 895人完成内镜筛查，筛查率为33.12%，高危人群的筛查率随年龄的增长呈现上升趋势（P<0.01）。内镜筛查共检出癌前病变462例，癌前病变检出率为1.78%；检出阳性病例156例，检出率为0.60%；随年龄的增加，癌前病变及阳性病例的检出率均呈现上升趋势（P均<0.01）。阳性病例中112例为早期病例，早诊率为71.79%。［结论］ 江苏省淮河流域胃癌早诊早治项目的检出率和早诊率高于全国多个地区，工作效果较好。未来的工作重心仍是精准识别高危人群，对其进行胃癌筛查工作，及时发现早期病变，提高人群早诊率。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze endoscopic gastric cancer screening results of the Early Diagnosis and Treatment Program in Huaihe River basin of Jiangsu Province from 2007 to 2021. ［Methods］ Cluster sampling method was used to select residents aged 40~69 years old in Huaihe River basin for cancer risk assessment， those individuals identified as high-risk received endoscopic indigo carmine staining and pathological biopsies. The Chi-square test was used to analyze the differences between the high-risk rate， screening rate and detection rate among different groups， and the trend Chi-square test was used to analyze the trend changes of high-risk rate， screening rate and detection rate in different years. ［Results］ From 2007 to 2021， 131 340 residents were recruited in the program and underwent the questionnaire risk assessment， 78 191 individuals were assessed as high risk with a high-risk rate of 59.53%. There were statistically significant differences in risk rates among different age groups(P<0.01)， and the high-risk rate was increased with the age(P<0.01). A total of 25 895 high-risk individuals received endoscopic examination， with a compliance rate of 33.12%. There were statistically significant differences in gastroscopy compliance rates among different age groups(P<0.01)， and the compliance rate was increased with the age(P<0.01). A total of 462 cases of precancerous lesions were detected in endoscopic examinations， with a detection rate of precancerous lesions of 1.78%； 156 cases of cancer were detected with a detection rate of 0.60%； with the increase of age， the detection rate of precancerous lesions and cancer cases was increased(both P<0.01). Among the cancer cases， 112 were early cases with an early diagnosis rate of 71.79%. ［Conclusion］ The detection rate and early diagnosis rate of Gastric Cancer Early Diagnosis and Treatment Program in the Huaihe River basin of Jiangsu Province are higher than those in many regions of the country； and the study shows that the program is effective in early detection of the precancerous lesions and gastric cancer. The focus of future work is still to accurately identify high-risk groups and screen them for gastric cancer， so as to detect early lesions in time and improve the quality of life of the population. |
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