刘 佳,陈 琼,刘曙正,等.2018年河南省白血病流行特征及2010—2018年变化趋势分析[J].中国肿瘤,2023,32(8):582-588.
2018年河南省白血病流行特征及2010—2018年变化趋势分析
Incidence and Mortality of Leukemia in Henan Province in 2018 and Its Change Trend from 2010 to 2018
投稿时间:2023-03-10  
DOI:10.11735/j.issn.1004-0242.2023.08.A003
中文关键词:  白血病  肿瘤登记  发病率  死亡率  河南
英文关键词:leukemia  cancer registration  incidence  mortality  Henan
基金项目:
作者单位
刘 佳 郑州大学附属肿瘤医院/河南省肿瘤医院 
陈 琼 郑州大学附属肿瘤医院/河南省肿瘤医院 
刘曙正 郑州大学附属肿瘤医院/河南省肿瘤医院 
徐慧芳 郑州大学附属肿瘤医院/河南省肿瘤医院 
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中文摘要:
      摘 要:[目的] 分析2018年河南省白血病流行特征及2010—2018年变化趋势。[方法] 收集、整理2010—2018年河南省白血病发病和死亡数据,按性别和年龄组分层估算2018年河南省白血病发病/死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、0~74岁累积发病/死亡率,应用年度变化百分比(annual percentage change,APC)分析2010—2018年河南省白血病发病率和死亡率的变化趋势。[结果] 据估计,2018年河南省共有4 947例白血病新发病例,粗发病率为4.54/10万,中标率为4.04/10万,世标率为4.15/10万,累积发病率(0~74岁)为0.38%,发病例数占全部癌症新发病例数的1.73%。共有3 107例白血病死亡病例,粗死亡率为2.85/10万,中标率为2.41/10万,世标率为2.38/10万,累积死亡率(0~74岁)为0.23%,死亡病例数占全部癌症死亡病例数的1.85%。男性白血病中标发病率和中标死亡率均高于女性,城市地区白血病中标发病率高于农村地区。2010—2018年河南省白血病发病率(APC=-2.7%,95%CI:-4.3%~-1.1%)与死亡率(APC = -2.7%,95%CI:-4.6%~-0.8%)均呈显著下降趋势(P均<0.05)。[结论] 2010—2018年河南省白血病发病率、死亡率均呈下降趋势,但由于河南省人口基数大,白血病防控仍不容忽视。
英文摘要:
      Abstract:[Purpose] To analyze the incidence and mortality of leukemia in 2018 and trends from 2010 to 2018 in Henan. [Methods] The data of leukemia new cases and deaths in Henan from 2010 to 2018 were collected and analyzed. The incidence/mortality rate, age-standardized incidence/mortality rate by Chinese standard population in 2000(ASIRC, ASMRC), age-standardized incidence/mortality rate by Segi’s world population(ASIRW, ASMRW), and cumulative incidence/mortality rate(0~74 years old) were calculated. The annual percentage change(APC) was used to analyze the trend of incidence and mortality in Henan from 2010 to 2018. [Results] It was estimated that there were 4 947 new cases of leukemia in Henan Province in 2018, accounting for 1.73% of all new cancer cases. The crude incidence rate of leukemia was 4.54/105, and the ASIRC and ASIRW were 4.04/105 and 4.15/105, respectively. The cumulative incidence rate of 0~74 years old was 0.38%. There were 3 107 leukemia deaths in 2018, accounting for 1.85% of all cancer deaths. The crude mortality rate was 2.85/105, ASMRC and ASMRW were 2.41/105 and 2.38/105. The cumulative mortality rate of 0~74 years old was 0.23%. The ASIRC and ASMRC of leukemia in male were higher than those in female. The ASIRC of leukemia in urban areas was higher than that in rural areas. The incidence(APC=-2.7%, 95%CI: -4.3%~-1.1%) and mortality(APC=-2.7%, 95%CI: -4.6%~-0.8%) of leukemia in Henan Province from 2010 to 2018 showed a significant downward trend(P<0.05). [Conclusion] The incidence and mortality of leukemia in Henan showed a downward trend from 2010 to 2018. However, with a large population base, the prevention and control of leukemia still cannot be ignored.
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