| 杜新宇,梁 迪,师 金,等.2016—2022年河北省城市居民上消化道癌筛查和随访结果分析[J].中国肿瘤,2023,32(6):414-422. |
| 2016—2022年河北省城市居民上消化道癌筛查和随访结果分析 |
| Results of Upper Gastrointestinal Cancer Screening and Follow-Up Among Urban Residents in Hebei Province from 2016 to 2022 |
| 投稿时间：2023-02-18 |
| DOI：10.11735/j.issn.1004-0242.2023.06.A003 |
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| 中文关键词: 上消化道癌 筛查 早诊早治 河北 |
| 英文关键词:upper gastrointestinal cancer screening early diagnosis and treatment Hebei |
| 基金项目:河北省自然科学基金京津冀联合基金项目（H2020206644） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2016—2022年河北省城市癌症早诊早治项目的上消化道癌筛查和随访数据。［方法］ 按照河北省城市癌症早诊早治中上消化道癌筛查流程，在石家庄市、唐山市、邢台市和邯郸市社区选定年龄40～74岁的当地居民，通过问卷调查之后采用国家癌症中心依据“哈佛癌症风险指数”设计的统一评估模型评估出高危人群，进一步通过内镜检查、病理活检以及随访，发现上消化道癌病变情况。将上消化道癌确诊病例分为筛查组与未筛查组，对两组病理特征进行对比分析。［结果］ 2016—2022年共计对河北省210 381名居民进行了高危评估，其中47 748人被评估为上消化道癌高危，高危率为22.70%。11 946人参与了内镜检查，参与率为25.02%。经过病理诊断，共检出了31例胃癌，12例食管癌，229例胃癌癌前病变，62例食管癌癌前病变，检出率分别为0.26%、0.10%、1.92%、0.52%。经过初筛和随访后，共计473例确诊为上消化道癌，累积发病率为0.22%，其中筛查组为66例，累积发病率为0.55%；未筛查组为407例，累积发病率为0.21%。筛查组的早期（0期+Ⅰ期）胃癌和食管癌确诊患者分别占66.67%和64.29%，均远高于未筛查组（分别为19.57%和22.92%）。［结论］ 筛查可以发现早期上消化道癌，提高检出率。然而，河北省城市居民上消化道癌筛查参与率仍有待提高，需加强对上消化道癌筛查知识的宣传与普及，增强居民的防癌意识。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of screening and follow-up of upper gastrointestinal cancer among urban residents in Hebei Province from 2016 to 2022. ［Methods］ According to the early diagnosis and treatment of upper gastrointestinal cancer project in Hebei Province， urban residents aged 40 to 74 years old in selected communities in Shijiazhuang， Tangshan， Xingtai and Handan cities participated in the screening program. The cancer risks were assessed through a questionnaire designed by the National Cancer Center based on the Harvard Cancer Risk Index. For high-risk subjects， the endoscopic examination， pathological biopsy and follow-up were conducted to detect precancerous lesions and upper gastrointestinal cancers. The confirmed cases of upper gastrointestinal cancer were divided into screening and non-screening groups， and the pathological characteristics of the two groups were compared. ［Results］ A total of 210 381 residents in Hebei Province participated in cancer risk assessment from 2016 to 2022， and 47 748 people were at high risk of upper gastrointestinal cancer with a high risk rate of 22.70%. Among them， 11 946 people participated in endoscopy examination with a participation rate of 25.02%. Confirmed by pathological examination， 31 cases of gastric cancer， 12 cases of esophageal cancer， 229 cases of gastric precancerous lesions， and 62 cases of esophageal precancerous lesions were detected， the detection rates were 0.26%， 0.10%， 1.92%， 0.52%， respectively. Through the preliminary screening and follow-up， a total of 473 cases were diagnosed with upper gastrointestinal cancer， and the cumulative incidence rate was 0.22%. There were 66 cases in the screening group with a cumulative incidence rate was 0.55%； 407 cases in the non-screening group， with a cumulative incidence rate of 0.21%. The early stage cases of gastric cancer and esophageal cancer in screening group accounted for 66.67% and 64.29%， respectively， which were significantly higher than those in non-screening group (19.57% and 22.92%). ［Conclusion］ Screening is conducive to find the early stage upper gastrointestinal cancer and improve the detection rate. However， the participation rate of screening among urban residents in Hebei Province need to be improved. It is necessary to strengthen the popularization of the knowledge of upper gastrointestinal cancer screening and enhance the health education of cancer prevention consciousness. |
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