| 杜 佳,张 艳,郭 晴,等.2012—2020年重庆城市居民肝癌筛查结果分析[J].中国肿瘤,2022,31(11):909-914. |
| 2012—2020年重庆城市居民肝癌筛查结果分析 |
| Results of Liver Cancer Screening Among Urban Resident in Chongqing， 2012—2020 |
| 投稿时间：2022-04-18 |
| DOI：10.11735/j.issn.1004-0242.2022.11.A010 |
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| 中文关键词: 肝癌 癌症筛查 高危人群 早诊早治 城市居民 重庆 |
| 英文关键词:liver cancer cancer screening high risk population early diagnosis and treatment urban resident Chongqing |
| 基金项目:重庆市科研机构绩效激励引导专项(cstc2018jxjl130058) |
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| 中文摘要: |
| 摘 要：［目的］ 分析2012—2020年重庆城市居民肝癌筛查结果，为肝癌防治工作提供依据和建议。［方法］ 动员重庆市40～74岁城市户籍居民自愿参加肝癌危险因素调查和肝癌风险评估，并对评估出的肝癌高危人群联合应用血清甲胎蛋白（AFP）检测和腹部超声检查，分析城市居民肝癌高危率、筛查参与率和肝病变检出率。［结果］ 本研究期间共完成问卷调查和高危人群评估352 005人，评估出肝癌高危人群41 800人（高危率11.87%），完成肝癌筛查19 957人（筛查参与率47.74%），检出疑似肝癌8例（检出率0.04%）、肝占位性病变199例（1.00%）、肝硬化92例（0.46%）、AFP阳性286例（1.43%）、脂肪肝5 267例（26.39%）。男性肝占位性病变（1.18%）、肝硬化（0.71%）和脂肪肝（30.92%）检出率显著高于女性（0.86%、0.28%和23.07%）；70～74岁组疑似肝癌检出率最高（0.41%）。［结论］ 采用AFP检测结合腹部超声检查的筛查手段，有助于及时了解居民肝脏健康状况，早期发现病变。此外，应努力提高居民肝癌筛查参与率，提升项目点县(市、区)的组织、宣传和服务能力，以提高筛查效益。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the results of liver cancer screening among urban residents in Chongqing from 2012 to 2020. ［Methods］ Epidemiological investigation and liver cancer risk assessment were conducted among urban residents aged 40～74 years old during 2012 to 2020. People with high risk of liver cancer received serum alpha-fetoprotein(AFP) detection combined with abdominal ultrasonography examination. The liver cancer high risk rate， screening rate and detection rate were calculated. ［Results］ A total of 352 005 residents completed the questionnaire survey and liver cancer risk assessment， and 41 800 were identified as high risk individuals(11.87%）， among whom 19 957 received screening tests with a compliance rate of 47.74%. Eight cases of suspected liver cancer were detected with a detection rate of 0.04%； 199 cases of hepatic space occupying lesion were detected with a detection rate of 1.00%； 92 cases liver cirrhosis were detected with a detection rate of 0.46%； 286 cases AFP positive were detected with a detection rate of 1.43%； 5 267 cases of fatty liver were detected with a detection rate of 26.39%. The detection rates of hepatic space occupying lesion(1.18%)， liver cirrhosis(0.71%) and fatty liver(30.92%) in male were higher than those in female(0.86%， 0.28% and 23.07%). The 70～74 years old group has the highest detection rate of suspected liver cancer(0.41%). ［Conclusion］ Liver cancer screening program including risk assessment and AFP detection combined with abdominal ultrasonography can help to detect liver cancer and other liver diseases in general population. |
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