| 姚丽萍,袁浩冉,刘玉琴.2018年甘肃省肿瘤登记地区卵巢癌流行特征及2010—2018年变化趋势分析[J].中国肿瘤,2022,31(7):549-555. |
| 2018年甘肃省肿瘤登记地区卵巢癌流行特征及2010—2018年变化趋势分析 |
| Incidence and Mortality of Ovarian Cancer in Cancer Registration Areas of Gansu Province in 2018 and Its Trend from 2010 to 2018 |
| 投稿时间：2022-03-23 |
| DOI：10.11735/j.issn.1004-0242.2022.07.A006 |
|
 |
| 中文关键词: 卵巢癌 发病率 死亡率 趋势 甘肃 |
| 英文关键词:ovarian cancer incidence mortality trend Gansu |
| 基金项目: |
|
| 摘要点击次数: 428 |
| 全文下载次数: 99 |
| 中文摘要: |
| 摘 要：［目的］ 分析2018年甘肃省肿瘤登记地卵巢癌发病与死亡情况及2010—2018年卵巢癌趋势变化。［方法］ 按照国家癌症中心制定的数据质量审核评价标准，对甘肃省符合质量控制标准要求的15个肿瘤登记点上报的卵巢癌发病、死亡和人口数据进行汇总分析。按城乡和年龄组分层计算发病（死亡）率、标化发病（死亡）率、0~74岁累积率等统计指标。中标率及世标率分别采用2000年全国普查标准人口年龄构成和Segi’s世界标准人口年龄构成计算。利用Joinpoint线性回归模型分析计算2010—2018年甘肃省肿瘤登记地区卵巢癌发病率、死亡率的年度变化百分比（APC）。［结果］ 2018年甘肃省肿瘤登记地区卵巢癌粗发病率为8.09/10万，中标率为6.21/10万，世标率为6.41/10万，累积率（0~74岁）为0.69%，占女性全部恶性肿瘤发病的3.57%，居女性恶性肿瘤发病的第10位。卵巢癌粗死亡率为1.95/10万，中标率为1.36/10万，世标率为1.48/10万，累积率（0~74岁）为0.19%，占女性全部恶性肿瘤死亡的1.84%，居女性恶性肿瘤死亡的第13位。发病率和死亡率分别在45岁和40岁开始随年龄增长呈上升趋势，高峰均在70~74岁年龄组。2010—2018年甘肃省肿瘤登记地区卵巢癌中标发病率及中标死亡率均呈下降趋势（APC=-0.95%，95%CI：-7.10%~5.60%；APC=-1.93%，95%CI：-14.60%~12.60%），差异均无统计学意义（P>0.05）。在地区分布中天祝藏族自治县卵巢癌中标发病率最高，会宁县中标死亡率最高；古浪县中标发病率与死亡率最低。［结论］ 甘肃省肿瘤登记地区卵巢癌发病率仍处我国较高水平，应根据年龄和地区分布差异，采取针对性措施，积极制订卵巢癌防治策略，降低卵巢癌对女性人群的危害。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the incidence and mortality of ovarian cancer in the cancer registration areas of Gansu Province in 2018 and the trends from 2010 to 2018. ［Methods］ The incidence， mortality and population data of female ovarian cancer reported by 15 cancer registries in Gansu Province that met the requirements of quality control standards were analyzed. The incidence(mortality) rate， age-standardized incidence(mortality) rate， cumulative rate(0~74 years old) were calculated by area distribution(urban and rural) and age groups. The age-standardized rate was adjusted by Chinese standard population in 2000(ASIRC， ASMRC) and world standard(Segi’s) population(ASIRW， ASMRW)， respectively. Joinpoint linear regression model was used to calculate the annual percentage change(APC) of the incidence and mortality of ovarian cancer from 2010 to 2018. ［Results］ In 2018， the crude incidence of ovarian cancer among women in the cancer registration area of Gansu Province was 8.09/105， ASIRC and ASIRW were 6.21/105 and 6.41/105， respectively， and the cumulative rate(0~74 years old) was 0.69%， accounting for 3.57% of all malignant cancers in women and ranking 10th in the incidence. The crude mortality rate was 1.95/105， ASIRC and ASIRW were 1.36/105 and 1.48/105， respectively， and the cumulative rate(0~74 years old) was 0.19%， accounting for 1.84% of all malignant tumors in women， ranking 13th in all cancers in women. The incidence and mortality began to increase at the age of 45 and 40， respectively， and the peaks were in the age group of 70~74 years. From 2010 to 2018， the incidence and mortality of women with ovarian cancer in the cancer registration area of Gansu Province showed downward trends(APC=-0.95%， 95%CI： -7.10%~5.60%； APC=-1.93%， 95%CI： -14.60%~12.60%)， but the difference was not statistically significant(P>0.05). In the regional distribution， Tianzhu Tibetan Autonomous County had the highest morbidity rate， Huining County had the highest mortality rate； while Gulang County had the lowest incidence and mortality rates. ［Conclusion］ The incidence of ovarian cancer among women in the cancer registration areas of Gansu Province is still at a relatively high level nationwide. Targeted measures should be taken according to age and regional distribution for the prevention and treatment of ovarian cancer in women. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|