| 杜 佳,张 艳,刘 秀.2012—2019年重庆市城市居民结直肠癌筛查结果分析[J].中国肿瘤,2022,31(5):355-360. |
| 2012—2019年重庆市城市居民结直肠癌筛查结果分析 |
| Screening Results of Colorectal Cancer Among Urban Residents in Chongqing Municipality from 2012 to 2019 |
| 投稿时间：2021-10-19 |
| DOI：10.11735/j.issn.1004-0242.2022.05.A006 |
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| 中文关键词: 结直肠癌 高危人群 早诊早治 筛查 重庆 |
| 英文关键词:colorectal cancer high-risk population early diagnosis and early treatment screening Chongqing |
| 基金项目:重庆市科学技术局科研机构绩效激励引导专项(cstc2018jxjl130058) |
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| 中文摘要: |
| 摘 要：［目的］ 分析2012—2019年重庆市城市癌症早诊早治项目参与居民结直肠癌查结果。［方法］ 通过结直肠癌危险因素调查和风险评估，确定结直肠癌高危人群，对高危人群进行肠镜检查和必要性病理活检，分析结直肠癌的高危率、肠镜筛查依从性和各种病变检出率。［结果］ 2012—2019年间共287 794人完成结直肠癌危险因素调查和风险评估，36 264人被评估为结直肠癌高危人群，高危率为12.60%，其中6 849人接受肠镜筛查（依从性为18.89%），完成活检1 731人（活检率为25.27%）。经病理确诊，检出结直肠癌11例、癌前病变331例、非进展期腺瘤696例、非瘤性息肉338例，检出率分别为0.16%（11/6 849）、4.83%（331/6 849）、10.16%（696/6 849）和4.94%（338/6 849）。女性结直肠癌高危率高于男性，且年龄组间差异明显；男性依从性高于女性，随年龄组增高而下降；男性活检率和各病变检出率均高于女性，且随年龄增高而呈现上升趋势。［结论］ 对于重庆市结直肠癌高危人群，应加强宣传教育，进一步提高肠镜检查依从性。通过癌症风险评估系统确定结直肠癌高危人群，对高危人群进行肠镜检查是提高结直肠癌检出率和筛查成本效益的重要途径。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of colorectal cancer screening among urban population in Chongqing Municipality from 2012 to 2019. ［Methods］ The colorectal cancer screening program was conducted among urban residents of Chongqing Municipality from 2012 to 2019. The risk assessment was performed and the identified high-risk subjects for colorectal cancer were subject to colonoscopy examination. The high-risk rate of colorectal cancer， compliance rate of colonoscopy and detection rate were analyzed. ［Results］ A total of 287 794 residents participated in questionnaire risk assessment， and 36 264 were identified as high-risk subjects of colorectal cancer with a high-risk rate of 12.60%， among whom 6 849 underwent colonoscopy with a compliance rate of 18.89%， including 1 731 received biopsy(25.27%). The detection rates of colorectal cancer， colorectal precancerous lesions， non-progressive adenoma and non-neoplastic polyps were 0.16%(11/6 849)， 4.83%(331/6 849)， 10.16%(696/6 849) and 4.94%(338/6 849)， respectively. The high-risk rate of females was significantly higher than that of males， and showed significant differences among age groups. The colonoscopy compliance rate of males was significantly higher than that of females， and decreased with age. The biopsy rate and the detection rate of lesions among males were significantly higher than those of females， and increased with age. ［Conclusion］ For colorectal cancer screening program among urban residents in Chongqing Municipality， the the compliance of colonoscopy among high-risk population is relatively low， and the public education on the importance of colonoscopy need to be improved. |
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