| 刘 茵,陈 琼,张璐瑶.2017年河南省肝癌流行现状及2010—2017年趋势分析[J].中国肿瘤,2022,31(5):335-340. |
| 2017年河南省肝癌流行现状及2010—2017年趋势分析 |
| Incidence and Mortality of Liver Cancer in 2017 and Its Trend from 2010 to 2017 in Henan Province |
| 投稿时间：2021-12-20 |
| DOI：10.11735/j.issn.1004-0242.2022.05.A003 |
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| 中文关键词: 肝癌 发病率 死亡率 趋势 河南 |
| 英文关键词:liver cancer incidence mortality trend Henan |
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| 中文摘要: |
| 摘 要：［目的］ 分析河南省肝癌2017年发病、死亡现状及2010—2017年发病、死亡变化趋势。［方法］ 利用河南省肿瘤登记处上报的、质控合格的肝癌发病与死亡资料，结合全省户籍人口数据，估算2017年分城乡、性别、年龄组别发病与死亡率、构成比、中标率、世标率和累积率（0~74岁），分析2010—2017年河南省肝癌中标发病（死亡）率的年均变化百分比（AAPC）及其95%置信区间（CI）。［结果］ 2017年河南省肝癌新发病例数估计为31 508例，死亡病例数估计为26 732例。2017年河南省肝癌发病率为29.10/10万，中标率为21.62/10万，世标率为21.45/10万，累积率（0~74岁）为2.45%。2017年河南省肝癌死亡率为24.69/10万，中标率为17.77/10万，世标率为17.88/10万，累积率（0~74岁）为2.00%。中标发病率和死亡率均呈现农村高于城市地区、男性高于女性的特点。肝癌年龄别发病率和死亡率均随年龄增加而上升，在85+岁达到峰值。2010—2017年，河南省肝癌中标发病（死亡）率整体均呈平稳趋势，城市地区中标发病率呈显著下降趋势（AAPC=-2.3%，95%CI：-4.3%~-0.1%）。［结论］ 河南省肝癌疾病负担严重，整体发病率与死亡率均未出现明显下降趋势，应继续加强肝癌防控，对重点人群实施干预，推进筛查与早诊早治等工作。 |
| 英文摘要: |
| Abstract： ［Purpose］ To estimate the incidence and mortality of liver cancer in Henan Ｐrovince in 2017 and analyze its trend from 2010 to 2017. ［Methods］ The qualified data of liver cancer between 2010 and 2017 were collected from Henan Cancer Registration and Follow-up System. Combined with the census data， the crude rate， proportion， age-standardized rate by Chinese standard population in 2000， age-standardized rate by world population(Segi’s)， and cumulative rate(0~74 years old) of incidence and mortality of liver cancer by urban and rural population， gender and age-groups were estimated. The average annual percentage change(AAPC) and its 95% confidence interval(CI) of age-standardized incidence and mortality rate by Chinese population in 2000(ASIRC， ASMRC) from 2010 to 2017 were analyzed. ［Results］ In 2017， it was estimated that there were 31 508 new cases and 26 732 deaths of liver cancer in Henan Province. The incidence was 29.10/105， with the ASIRC of 21.62/105 and age-standardized incidence rates by world population(ASIRW) of 21.45/105. The cumulative incidence(0~74 years old) was 2.45%. The mortality rate was 24.69/105， with ASMRC of 17.77/105 and the age-standardized mortality rate by world population(ASMRW) of 17.88/105. The cumulative mortality(0~74 years old) was 2.00%. The ASIRC and ASMRC were all higher in rural areas than those in urban areas， and higher in male than those in female. The age-specific incidence and the age-specific mortality reached the peak at the age group of 85+. From 2010 to 2017， the ASIRC and ASMRC showed a steady trend， while a downward trend was observed in the incidence rate in urban areas(AAPC=-2.3%， 95%CI：-4.3%~-0.1%). ［Conclusion］ The incidence and mortality of liver cancer are high in Henan Province. It is critical to strengthen the prevention and control， carry out the targeted intervention， and promote screening and early diagnosis and treatment. |
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