徐杰茹,陈 磊,张 敏.1990—2019年中国卵巢癌发病与死亡趋势及其年龄-时期-队列模型分析[J].中国肿瘤,2022,31(4):276-283.
1990—2019年中国卵巢癌发病与死亡趋势及其年龄-时期-队列模型分析
Analysis on Incidence and Mortality Trend and Age-period-cohort of Ovarian Cancer in China from 1990 to 2019
投稿时间:2021-11-09  
DOI:10.11735/j.issn.1004-0242.2022.04.A005
中文关键词:  卵巢癌  发病率  死亡率  年龄-时期-队列模型  中国
英文关键词:ovarian cancer  incidence  mortality  age-period-cohort model  China
基金项目:国家自然科学基金(81673107)
作者单位
徐杰茹 南华大学公共卫生学院 
陈 磊 南华大学公共卫生学院 
张 敏 南华大学公共卫生学院 
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中文摘要:
      摘 要:[目的] 分析1990—2019年中国卵巢癌发病与死亡现状及其流行趋势。[方法] 收集并整理全球健康数据交换数据库(the Global Health Data Exchange,GHDx)中1990—2019年20~<85岁中国卵巢癌的发病与死亡数据,利用Joinpoint线性回归模型分析卵巢癌发病与死亡的变化趋势,并计算年度变化百分比(APC)与平均年度变化百分比(AAPC)值。运用年龄-时期-队列模型分析年龄、时期、队列对发病率与死亡率变化的影响。[结果] 1990—2019年中国卵巢癌发病率与死亡率均呈上升趋势,分别平均每年上升3.85%、3.86%。模型结果显示,发病与死亡的净漂移值均>0,分别为1.82%、0.89%。发病与死亡风险随年龄和时期的增加而增高,其队列效应表现不同,出生越晚的人群发病风险高,死亡风险低。[结论] 1990—2019年中国卵巢癌总体发病与死亡率均呈上升趋势,生活时代越近的老年人群发病与死亡的风险越高,对卵巢癌的防治工作应加强关注。
英文摘要:
      Abstract: [Purpose] To analyze the incidence and mortality of ovarian cancer and trends in China from 1990 to 2019. [Methods] The data of incidence and death of ovarian cancer among Chinese women aged 20~<85 from 1990 to 2019 were colleced from the Global Health Data Exchange (GHDx). Joinpoint linear regression model was used to analyze the change trends of ovarian cancer incidence and death, and the annual percentage change(APC) and average annual percentage change(AAPC) values were calculated. Use the age-period-cohort model to analyze the effects of age, period and cohort on changes in incidence and mortality. [Results] From 1990 to 2019, the incidence and mortality of ovarian cancer both showed an upward trend, with an average annual increase of 3.85% and 3.86%, respectively. The results of the age-period-cohort model showed that the net drift values of incidence and mortality were 1.82% and 0.89%, respectively. The risk of incidence and mortality increased with age and period. The cohort effect was different. People who were born later had a higher risk of incidence and a lower risk of mortality. [Conclusion] From 1990 to 2019, the overall incidence and mortality of female ovarian cancer in China are on the upward trend. The risk of incidence and mortality of ovarian cancer in modern life is high, and attention should be paid to the prevention and treatment of ovarian cancer.
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