| 卜 凡,杨金华,曹纳新.1987—2018年浙江省嘉善县女性乳腺癌发病趋势及病理学特征分析[J].中国肿瘤,2022,31(1):43-48. |
| 1987—2018年浙江省嘉善县女性乳腺癌发病趋势及病理学特征分析 |
| Trends of Incidence of Female Breast Cancer in Jiashan County of Zhejiang Province， 1987—2018 |
| 中文关键词 修订日期：2021-10-25 |
| DOI：10.11735/j.issn.1004-0242.2022.01.A004 |
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| 中文关键词: 乳腺癌 发病率 趋势 病理特征 浙江 |
| 英文关键词:breast cancer incidence rate trend pathological features Zhejiang |
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| 中文摘要: |
| 摘 要：［目的］ 了解浙江省嘉善县1987—2018年女性乳腺癌发病情况、变化趋势和病理特征。［方法］ 利用嘉善县肿瘤登记报告系统收集1987—2018年女性乳腺癌的登记资料。计算各年份、各年龄组女性乳腺癌粗发病率及标化发病率，中国人口标化发病率（中标率）按2010年第6次全国人口普查标准人口构成进行标化，世界人口标化发病率（世标率）按Segi’s世界标准人口构成进行标化。采用Joinpoint模型分析乳腺癌发病率、年度变化百分比（APC），采用构成比分析乳腺癌主要病理分型特征。［结果］ 1987—2018年嘉善县共登记报告女性乳腺癌新发病例2 034例，年均发病率33.52/10万，中标率30.32/10万，世标率22.67/10万。30年间发病总体呈上升趋势，1987—1997年相对稳定；1998—2008年，于45～岁达到发病高峰（P＜0.001）；2009—2018年，于25～岁年龄组开始呈增长趋势（P＜0.001），至45～岁年龄组达到最高峰（P＜0.001）。1987—1997年、1998—2008年、2009—2018年3个10年段中发病第1位次均为导管癌，且发病率呈上升趋势（P＜0.001）。［结论］ 嘉善县女性乳腺癌发病呈明显上升趋势，病理类型以导管癌为主。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the trends of incidence of female breast cancer in Jiashan County from 1987 to 2018. ［Methods］ The data of female breast cancer from 1987 to 2018 were collected from the tumor registration and reporting system in Jiashan County. The crude incidence rate and standardized incidence rate of female breast cancer in different years and age groups were compared. The age-standardized incidence rate by Chinese population(ASIRC) was adjusted by the sixth national census population(2010)， and the age-standardized incidence rate by world standard population(ASIRW) was adjusted by Segi’s population. The annual percentage change(APC) of female breast cancer incidence was analyzed by Joinpoint model. ［Results］ From 1987 to 2018， a total of 2 034 new cases of female breast cancer were registered in Jiashan County. The annual crude incidence rate was 33.52/105， and the ASIRC was 30.32/105， ASIRW was 22.67/105. From 1987 to 2018， the ASIRC showed a rising trend with an APC of 6.0%. From 1987 to 1997， the incidence was stable； from 1998 to 2008， it reached the peak at the age group of 45～ years old(P＜0.001)；from 2009 to 2018， it began to show an increasing trend in the age group of 25～ years old(P＜0.001)， and reached the peak in the age group of 45～ years old(P＜0.001). The most common pathological type was ductal carcinoma. ［Conclusion］ Female breast cancer in Jiashan County shows a significant upward trend during 1987 to 2018， and the main pathological type was ductal carcinoma. |
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