| 唐 娴,许晓君,夏 亮.2012—2016年广东省肿瘤登记地区宫颈癌发病和死亡流行特征分析[J].中国肿瘤,2021,30(10):740-745. |
| 2012—2016年广东省肿瘤登记地区宫颈癌发病和死亡流行特征分析 |
| Analysis of Incidence and Mortality of Cervical Cancer in Guangdong Cancer Registration Areas， 2012—2016 |
| 中文关键词 修订日期：2021-06-21 |
| DOI：10.11735/j.issn.1004-0242.2021.10.A004 |
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| 中文关键词: 宫颈癌 发病率 死亡率 流行特征 广东 |
| 英文关键词:cervical cancer incidence mortality epidemiological feature Guangdong |
| 基金项目:广东省医学科研基金（A2013073） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2012—2016年广东省肿瘤登记地区宫颈癌发病和死亡的流行特征和变化趋势。［方法］ 利用广东省肿瘤登记地区2012—2016年收集的宫颈癌发病和死亡个案，统计分析宫颈癌发病和死亡的粗率、中标率、世标率、年龄别率、累积率（0～74岁）、截缩率（35～64岁）以及上述指标的年度变化百分比（APC）。［结果］ 2012—2016年广东省肿瘤登记地区宫颈癌的平均发病率、中标率、世标率、0～74岁累积率、35～64岁截缩率分别为14.25/10万、11.56/10万、10.76/10万、1.17%和26.48/10万，平均发病年龄52.21岁，50～54岁达发病高峰，随后下降。5年间宫颈癌发病率相对稳定，在13.50/10万~15.28/10万间波动，APC为1.5%（P>0.05），但15～44岁发病率呈下降趋势，APC为-3.2%（P<0.05），农村地区45~64岁发病率呈上升趋势，APC为5.1%（P<0.05）。同期，宫颈癌平均粗死亡率、中标率、世标率、累积率（0~74岁）、截缩率（35~64岁）分别为4.03/10万、2.84/10万、2.75/10万、0.32%和5.73/10万，年龄别死亡率随年龄增长而升高，在70～74岁（城市70～74岁、农村65～69岁）达到高峰。5年间宫颈癌死亡率呈上升趋势，从3.12/10万上升至4.57/10万，APC为9.5%（P<0.05）。农村宫颈癌的发病率和死亡率均高于城市。［结论］ 2012—2016年间广东省肿瘤登记地区宫颈癌发病水平相对稳定，而死亡率呈上升趋势；45岁及以上人群、农村地区是防控重点，应切实加强宫颈癌三级预防综合防控措施。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of cervical cancer in cancer registration areas of Guangdong province from 2012 to 2016. ［Methods］ The newly diagnosed cases and death cases of cervical cancer in cancer registration areas of Guangdong province from 2012 to 2016 were collected. The crude incidence and mortality， age-standardized incidence and mortality， age-specific incidence and mortality， cumulative rate(0～74 years old)， truncated rate(35～64 years old) and annual percentage change(APC) were calculated. ［Results］ During 2012 to 2016， the average crude incidence， age-standardized incidence by Chinese standard population(2000)， age-standardized incidence by Segi’s world standard population， cumulative incidence rate(0～74 years old)， truncated incidence rate(35～64 years old) were 14.25/105， 11.56/105， 10.76/105， 1.17% and 26.48/105， respectively. The average onset age was 52.21 years old. The age-specific incidence rose with age and peaked at 50～54 years old. In general， the incidence remained relatively stable during 2012 to 2016， APC was 1.5%(P＞0.05). However， the incidence of 15～44 years old declined(APC was -3.2%) and that of 45～64 years old rose(APC = 5.1%) in rural areas（P＜0.05）. The average crude mortality， age-standardized mortality by Chinese standard population(2000)， age-standardized mortality by Segi’s world standard population， cumulative mortality rate(0～74 years old)， truncated mortality rate(35～64 years old) were 4.03/105， 2.84/105， 2.75/105， 0.32% and 5.73/105， respectively. The mortality rose with age and peaked at 65～69 and 70～74 years old in rural and urban areas， respectively. During 2012 to 2016， the crude mortality rose from 3.12/105 to 4.57/105(APC=9.5%， P<0.05). Both the incidence and mortality of rural areas were higher than those in urban areas. ［Conclusion］ The cervical cancer incidence in cancer registration areas of Guangdong province was stable between 2012 and 2016， but the mortality increased significantly. We should focus on rural areas and the population aged 45 and above， and implement the three-level prevention and control strategy effectively. |
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