| 刘芳江,王一茸,蔡伟聪.2001—2018年广东省深圳市结直肠癌发病现状和趋势分析[J].中国肿瘤,2021,30(9):671-677. |
| 2001—2018年广东省深圳市结直肠癌发病现状和趋势分析 |
| The Incidence and Trend of Colorectal Cancer in Shenzhen City from 2001 to 2018 |
| 中文关键词 修订日期：2021-03-04 |
| DOI：10.11735/j.issn.1004-0242.2021.09.A006 |
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| 中文关键词: 结直肠癌 发病率 时间趋势 肿瘤登记 广东 |
| 英文关键词:colorectal cancer incidence time trend cancer register Guangdong |
| 基金项目:深圳市医疗卫生三名工程（SZSM201911015） |
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| 中文摘要: |
| 摘 要：［目的］ 探讨2001—2018年深圳市户籍居民结直肠癌发病趋势。［方法］根据深圳市2001—2018年肿瘤登记发病数据以及相应人口数据，分别计算结直肠癌的粗发病率、年龄别发病率、标化发病率（中国人口标化率和世界人口标化率）、累计发病率（0~74岁）、截缩发病率（35~64岁）。运用年度变化百分比（APC）对2001—2018年期间深圳市结直肠癌的发病变化趋势进行描述。［结果］深圳市户籍居民2001—2018年间结直肠癌新发病例共9 130例，粗发病率19.37/10万，中标率27.17/10万，世标率26.80/10万，累计发病率（0~74岁）为3.19%，截缩发病率（35~64岁）为39.68/10万。男性发病率高于女性，男女发病性别比为1.43∶1。从时间趋势看，结直肠癌发病率呈显著上升趋势，世标率从2001年的22.87/10万升至2018年的29.99/10万，APC为1.86%（P<0.05）。发病率随年龄增长而增高，从50岁开始快速上升，于80~84岁时达到发病高峰。分发病部位看，结肠癌发病率高于直肠癌；2001—2018年间结肠癌和直肠癌的粗发病率呈持续增长态势，APC分别为3.99%、1.69%（P均<0.05）。 ［结论］ 深圳市2001—2018年间结直肠癌发病呈持续增长趋势，应积极探索结直肠癌发病相关危险因素，加强早期筛查和综合干预防控研究，以期降低居民结直肠癌发病风险。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the incidence and trend of colorectal cancer in Shenzhen City from 2001 to 2018. ［Methods］ The colorectal cancer incidence data were collected from the Shenzhen Cancer Registry. Crude incidence， age-specific incidence， age-standardized rate by Chinese standard population in 2000 and Segi’s world population(ASR China and ASR world)， cumulative inciden rate(0~74 years)， truncated inciden rate(35~64 years). The annual percent-age change(APC) was calculated to estimate trends of colorectal cancer. ［Results］ From 2001 to 2018， the total new cases of colorectal cancer in Shenzhen City were 9 130. The crude incidence was 19.37/105， with ASR China of 27.17/105 and ASR world of 26.80/105. The cumulative rate(0~74 years) was 3.19%， and truncated rate(35~64 years) was 38.68/105. The incidence in male was significantly higher than that in female， with a sex ratio of 1.43∶1. From 2001 to 2018， the ASR world of colorectal cancer increased from 22.87/105 to 29.99/105， APC was 1.86%(P<0.05). The incidence of colorectal cancer increased with age. There was a substantial increase of the incidence after 50 years old， and the peak age of onset was at the age group of 80~84 years old. From 2001 to 2018， the incidence of colon cancer was higher than that of rectal cancer and the incidence of colon and rectal cancer both had a sustainable growth， the APC was 3.99%， 1.69%（both P<0.05）， respectively. ［Conclusion］ The incidence of colorectal cancer continuously increased from 2001 to 2018 in Shenzhen City. Comprehensive study on prevention and screening should be promoted to reduce the incidence of colorectal cancer. |
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