| 冯 祥,华召来,钱东福.2011—2017年江苏省扬中市上消化道癌高危人群食管、胃/贲门癌筛查结果分析[J].中国肿瘤,2021,30(7):523-528. |
| 2011—2017年江苏省扬中市上消化道癌高危人群食管、胃/贲门癌筛查结果分析 |
| Analysis of Screening Results of Esophageal，Stomach and Cardiac Cancer in High-risk Population of Upper Digestive Tract Cancer in Yangzhong City from 2011 to 2017 |
| 中文关键词 修订日期：2020-07-27 |
| DOI：10.11735/j.issn.1004-0242.2021.07.A007 |
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| 中文关键词: 上消化道肿瘤 内窥镜筛查 检出率 江苏 |
| 英文关键词:upper gastrointestinal cancer endoscopic screening detection rate Jiangsu |
| 基金项目:国家重点研发计划(2016YFC0901400、2016YFC1302800)；中国消化道早癌医师共同成长计划(GTCZ-2020-JS-32-0003)；镇江市社会发展指导性科技计划项目(FZ2020023) |
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| 中文摘要: |
| 摘 要：［目的］ 分析2011—2017年江苏省扬中市上消化道癌（食管、胃/贲门）筛查结果及其分布特征，旨在探索上消化道癌筛查的改进策略。［方法］ 2011—2017年在上消化道癌高发区江苏省扬中市采用整群抽样的方法，选取部分自然村中40~69岁户籍居民作为高危人群，共14 687人次，对其行内窥镜检查后，经病理学诊断确诊。［结果］ 食管、胃/贲门癌前病变检出率分别为2.32%（341/14 687）、0.55%（81/14 687）；重度不典型增生及以上病变检出率分别为0.52%（77/14 687）、0.55%（81/14 687），早期诊断率分别为77.92%（60/77）、61.73%（50/81）。男性各级病变检出率均高于女性（P<0.05），且各级病变检出率与年龄均成正相关（P<0.05）。从筛查年份来看，食管历年癌前病变检出率均高于胃/贲门，且前者上升趋势较为明显，两者重度不典型增生及以上病变检出率变化则较为平稳。［结论］ 上消化道癌高危人群筛查能够有效发现癌前病变及早期癌患者，对降低地区癌症发病率和死亡率有现实意义。可以通过提高男性及老年群体的筛查依从性优化筛查成效。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the screening results of upper digestive tract cancer(esophageal and gastric/cardia cancer) screening and its characters in Yangzhong City from 2011 to 2019. ［Methods］ The method of cluster sampling was used to select subjects aged 40～69 years from villages in the high-risk area of upper digestive tract cancer in Yangzhong City， Jiangsu Province. A total of 14 687 participants underwent diagnosis procedures by endoscopy and pathology. ［Results］ The detection rates of precancerous lesions of the esophageal and gastric/cardia cancer were 2.32%(341/14 687) and 0.55%(81/14 687)， respectively. The rates of severe dysplasia lesions and above were 0.52%(77/14 687) and 0.55%(81/14 687)， respectively， among which 77.92%(60/77) and 61.73%(50/81) were early stages of esophageal and gastric/cardia lesions， respectively. The detection rate of male lesions at all levels was higher than that of female(P<0.05). The detection rate of lesions at all levels was positively correlated with age(P<0.05). The detection rate of precancerous esophageal lesions was higher than that of stomach/cardia， and the former had a more apparent upward trend. In contrast， the detection rate of severe dysplasia and above among them was relatively stable. ［Conclusions］ Screening of the high-risk population can effectively detect patients with precancerous lesions and early esophageal and gastric/cardia cancers， which has practical significance to reduce cancer incidence and mortality in the region. Screening effectiveness can be optimized by increasing the screening compliance of men and the elderly. |
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